SOLASODINE
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SOLASODINE 속성
- 녹는점
- 200-202°
- 알파
- D25 -98° (c = 0.14 in methanol); D -113° (CHCl3)
- 끓는 점
- 532.75°C (rough estimate)
- 밀도
- 1.0159 (rough estimate)
- 굴절률
- 1.6400 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 용해성0.5mg/mL, 투명(가온)
- 산도 계수 (pKa)
- pKb 6.30(at 25℃)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- optical activity
- [α]/D -88 to -98°, c = 0.2 in methanol
- InChIKey
- KOZCINYDCJVLDW-GCGBSLFCSA-N
- CAS 데이터베이스
- 126-17-0(CAS DataBase Reference)
- NIST
- Solasodine(126-17-0)
안전
안전지침서 | 22-24/25 | ||
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RTECS 번호 | WF1300000 | ||
유해 물질 데이터 | 126-17-0(Hazardous Substances Data) |
SOLASODINE C화학적 특성, 용도, 생산
개요
There is still some doubt as to whether this base occurs as such in Solanum aviculare and S. xanthocarpum or whether it is an artifact formed from Sola_x0002_sonine (q.v.) during the extraction process. The base is laevorotatory having [α]20D - 92.4° (C6H6) and the following salts and derivatives have been prepared: hydrochloride, m.p. 314°C; hydriodide, m.p. 293°C; oxalate, m.p. 248°C; tartrate, m.p. 222°C; picrate, m.p. 1.4l-2°C; picrolonate, m.p. 234°C; acetyl derivative, m.p. 195°C; benzoyl compound, m.p. 2l6-7°C and the 3:5-dinitrobenzoyl derivative, m.p. 191.5-193°C. The alkaloid forms a sparingly soluble digitonide and yields Diels's hydrocarbon on selenium dehydrogenation.용도
Solasodine is a potentially useful precursor for steroidal compounds and hormones, this is usually found in plants from the solanaceae family. It also has potent cytotoxic and anti-inflammatory effects.일반 설명
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KGSafety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.Purification Methods
Solasodine crystallises (as monohydrate) from MeOH as lustrous plates (on heating, the plates change to needles as they melt and resolidify in needles), or aqueous 80% EtOH, and sublimes at high vacuum. After recrystallisation from H2O, m 198-199o, then from Me2CO/H2O, m 199-201o, it has [] D 22 -109.3o (c 0.581, CHCl3). On TLC with silica gel G (*C6H6/absolute EtOH, 8:2) it has RF 0.45. IR (KBr): max at 10.3, 10.4, 11.2, 11.5 (azaoxaspirane bands). [Schreiber & Rnsch Tetrahedron 20 1939 1964, Uhle J Org Chem 27 656 1962, Kessar et al. Tetrahedron 27 2153 1971, Beilstein 27 III/IV 2000.]참고 문헌
Rochelmeyer, Chen., Arch. Pharm., 277,329 (1939)Briggs., J. Chem. Soc., 3, (1942)
Briggs et al., ibid, 3013 (1950)
Absolute configuration: Boll, Phillipsborn., Acta Chem. Scand., 19, 1365 (1965)
Synthesis: Schreiber, Walther, Ronsch., Tetrahedron, 20, 1939 (1964)
Adam, Schreiber., Experientia, 21,471 (1965)
Adam, Schreiber., Tetrahedron, 22,3591 (1966)
SOLASODINE 준비 용품 및 원자재
원자재
Cryptogenin
Pregn-5-ene-3,16-diol, 20-[(5R)-3,4,5,6-tetrahydro-5-methyl-2-pyridinyl]-, 3,16-diacetate, (3β,16β,20S)-
Solasodine, hydrochloride
Furosta-5,20(22)-dien-3-ol, 26-amino-, (3β,25R)-
(20R,25R)-spirost-5-en-3beta-yl acetate
준비 용품
SOLASODINE 공급 업체
글로벌( 218)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 |
sales@zhswyy.com | China | 338 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
SOLASODINE 관련 검색:
아이소트리데칸아민 시트로넬롤 콜레스테롤
Solamargine
SOLASONINE
SOLASODINE
12-AMINO-1-DODECANOL
Cyclomethylenecitronellol
SEC-BUTYL ETHER
Cyclopentamine
2-heptyltetrahydrofuran
2-CYCLOPENTYL-ETHYLAMINE
(R)-(+)-BETA-CITRONELLOL
2-Nonanamine
SOLANIDINE
2-(1-methylethyl)piperidine
3-PIPERIDIN-2-YL-PROPAN-1-OL
CIS-6-OCTADECEN-1-OL