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THIOSTREPTON

THIOSTREPTON 구조식 이미지
카스 번호:
1393-48-2
상품명:
THIOSTREPTON
동의어(영문):
x146;a-8506;thiactin;bryamycin;THIOSTREPTON;THIOSTREPTION;antibioticx146;antibiotica8506;antibiotic6761-31;Thiostrepton (200 mg)
CBNumber:
CB5204768
분자식:
C72H85N19O18S5
포뮬러 무게:
1664.89
MOL 파일:
1393-48-2.mol

THIOSTREPTON 속성

녹는점
248-257°C (dec.)
알파
D23 -98.5° (glacial acetic acid); -61° (dioxane); -20° (pyridine)
밀도
1.0824 (rough estimate)
굴절률
1.6700 (estimate)
저장 조건
−20°C
용해도
Soluble in DMSO or chloroform
물리적 상태
Off-white powder
Merck
13,9440

안전

위험품 표기 Xn
위험 카페고리 넘버 22
안전지침서 22-24/25
WGK 독일 3
RTECS 번호 XN6300100
F 고인화성물질 10-21
HS 번호 29419090

THIOSTREPTON C화학적 특성, 용도, 생산

화학적 성질

Off-White Solid

용도

beta-adrenergic agonist

용도

Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S ribosomal subunit. Thiostrepton is an inducer of tipA, a gene that controls the bacterial transcription regulators, TipAL and TipAS, that are central regulators in multidrug resistance. Thiostrepton is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.

용도

Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S ribosomal subunit. Thiostrepton is an inducer of tipA, a gene that controls the bacterial transcription regulators, and TipAL and TipAS, that are central regulators in multidrug resistance. Thiostrepton is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.

용도

Natural antibiotic derived from Streptomyces.

용도

A protein synthesis-inhibiting antibiotic

정의

ChEBI: A heterodetic cyclic peptide, in which the cyclisation step involves a formal lactonisation between the carboxy group of a quinaldic acid-based residue and a secondary alcohol. An antibiotic that inhibits bacterial protein synthesis. Also acts as an antitu or agent.

THIOSTREPTON 준비 용품 및 원자재

원자재

준비 용품


THIOSTREPTON 공급 업체

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BOC Sciences
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Dalian Meilun Biotech Co., Ltd. 0411-66771943;0411-66771942
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010-65763397 waley188@sohu.com China 12341 58
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(86) 21-58955996 apisales@chemexpress.com.cn China 7559 61
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