아이소류신

아이소류신
아이소류신 구조식 이미지
카스 번호:
7004-09-3
한글명:
아이소류신
동의어(한글):
아이소류신
상품명:
Isoleucine
동의어(영문):
ISOLEUCINE
CBNumber:
CB52130861
분자식:
C6H13NO2
포뮬러 무게:
131.17
MOL 파일:
7004-09-3.mol

아이소류신 속성

녹는점
>166°C (dec.)
저장 조건
Refrigerator
용해도
수용액 (약간 용해됨), DMSO(약간 용해됨,초음파 처리)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
2.32(at 25℃)
색상
흰색에서 황백색까지

안전

아이소류신 C화학적 특성, 용도, 생산

개요

Isoleucine ( abbreviated as Ile or I ) is an α - amino acid with the chemical formula HO2CCH(NH2)CH(CH3)CH2CH3. It is an essential amino acid, which means that humans cannot synthesize it, so it must be ingested. Its codons are AUU, AUC and AUA.
With a hydrocarbon side chain, isoleucine is classified as a hydrophobic amino acid. Together with threonine, isoleucine is one of two common amino acids that have a chiral side chain. Four stereoisomers of isoleucine are possible, including two possible diastereomers of L-isoleucine. However, isoleucine present in nature exists in one enantiomeric form, (2S,3S)-2-amino-3-methylpentanoic acid.

화학적 성질

Crystals. Slightly soluble in water; nearly insoluble in alcohol; insoluble in ether.

출처

Even though this amino acid is not produced in animals, it is stored in high quantities. Foods that have high amounts of isoleucine include eggs, soy protein, seaweed, turkey, chicken, lamb, cheese, and fish.

용도

Amino acid.

정의

An essential amino acid, found naturally in the L(+) form.

Biosynthesis

As an essential nutrient, it is not synthesized in the body, hence it must be ingested, usually as a component of proteins. In plants and microorganisms, it is synthesized via several steps, starting from pyruvic acid and alpha - keto glutarate. Enzymes involved in this biosynthesis include :
Aceto lactate synthase (also known as aceto hydroxy acid synthase)
Aceto hydroxy acid iso meroreductase
Dihydroxy acid dehydratase
Valine amino transferase.

신진 대사

Isoleucine is both a glucogenic and a ketogenic amino acid. After transamination with alpha-ketoglutarate the carbon skeleton can be converted into either Succinyl CoA, and fed into the TCA cycle for oxidation or converted into oxaloacetate for gluconeogenesis (hence glucogenic). It can also be converted into Acetyl CoA and fed into the TCA cycle by condensing with oxaloacetate to form citrate. In mammals Acetyl CoA cannot be converted back to carbohydrate but can be used in the synthesis of ketone bodies or fatty acids, hence ketogenic.

아이소류신 준비 용품 및 원자재

원자재

준비 용품


아이소류신 공급 업체

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