ARZOXIFENE

ARZOXIFENE 구조식 이미지
카스 번호:
182133-25-1
상품명:
ARZOXIFENE
동의어(영문):
SERMIII;ARZOXIFENE;2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-benzothiophen-6-ol;2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]benzo[b]thiophene-6-ol;Benzo[b]thiophene-6-ol, 2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]-;3-[(4-{[2-(hexahydropyridin-1-yl)ethyl]oxy}phenyl)oxy]-2-(4-methoxyphenyl)benzo[b]thiophen-6-ol
CBNumber:
CB52451290
분자식:
C28H29NO4S
포뮬러 무게:
475.6
MOL 파일:
182133-25-1.mol

ARZOXIFENE 속성

녹는점
174-176°
끓는 점
656.4±55.0 °C(Predicted)
밀도
1.234
산도 계수 (pKa)
9.20±0.40(Predicted)

안전

ARZOXIFENE C화학적 특성, 용도, 생산

Clinical Use

Arzoxifene is a third-generation SERM currently in Phase III clinical trials for the treatm ent of ER-positive recurrent/metastatic breast cancer. Similar to raloxifene, it is an ER antagonist in both breast and uterine tissues and an ER agonist on bone and the cardiovascular system. Arzoxifene is able to both preserve and build bone mineral density, which makes it a viable candidate for the treatment of osteoporosis. Ample evidence from early clinical trials indicates that arzoxifene also can be utilized as a chemopreventive agent against breast cancer.

부작용

Adverse effects include hot flashes (major) and headache, nausea, vomiting, and constipation (minor).

ARZOXIFENE 준비 용품 및 원자재

원자재

준비 용품


ARZOXIFENE 공급 업체

글로벌( 20)공급 업체
공급자 전화 이메일 국가 제품 수 이점
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Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
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