4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline 구조식 이미지
카스 번호:
630125-91-6
상품명:
4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline
동의어(영문):
4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)aniline;4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline;Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-
CBNumber:
CB52627024
분자식:
C14H20F3N3
포뮬러 무게:
287.32
MOL 파일:
630125-91-6.mol

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline 속성

끓는 점
344.9±42.0 °C(Predicted)
밀도
1.195±0.06 g/cm3(Predicted)
저장 조건
under inert gas (nitrogen or Argon) at 2–8 °C
용해도
soluble in Dichloromethane;
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
7.76±0.10(Predicted)
색상
노란색

안전

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline C화학적 특성, 용도, 생산

용도

4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N''-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.

4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline 준비 용품 및 원자재

원자재

준비 용품


4-((4-ethylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)aniline 공급 업체

글로벌( 37)공급 업체
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Allfluoro pharmaceutical co. ltd.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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LEAPCHEM CO., LTD.
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Aladdin Scientific
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Amadis Chemical Company Limited
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ForeChem (Nantong) Technology Co.,Ltd. 513-85982855 18921614129
sales@xianxingpharm.com China 1819 61
Haoyuan Chemexpress Co., Ltd. 021-58950125
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Changzhou Chemscaler Pharmtech Co., Ltd. 0519-81096292 15312577869
chemscaler@yahoo.com.cn China 305 60
Cochemical Ltd. 029-86115547 17791676824
sales@cochemical.com China 3049 58
Bide Pharmatech Ltd. 400-1647117 15221909166
product02@bidepharm.com China 41438 60

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