2-Chloro-5-fluoropyrimidine
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2-Chloro-5-fluoropyrimidine 속성
- 끓는 점
- 149.0-162.0°C
- 밀도
- 1.439 g/mL at 20 °C (lit.)
- 굴절률
- n
20/D 1.503(lit.)
- 인화점
- 150 °F
- 저장 조건
- under inert gas (nitrogen or Argon) at 2-8°C
- 산도 계수 (pKa)
- -2.54±0.22(Predicted)
- 물리적 상태
- 액체
- 색상
- 무색~황색으로 투명함
- InChI
- InChI=1S/C4H2ClFN2/c5-4-7-1-3(6)2-8-4/h1-2H
- InChIKey
- AGYUQBNABXVWMS-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C(F)C=N1
- CAS 데이터베이스
- 62802-42-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 22-34-41-37/38 | ||
안전지침서 | 26-36/37/39-45 | ||
유엔번호(UN No.) | UN 2735 8/PG 2 | ||
WGK 독일 | 3 | ||
위험 참고 사항 | Harmful | ||
위험 등급 | IRRITANT | ||
위험 등급 | 8 | ||
포장분류 | Ⅲ | ||
HS 번호 | 29335990 |
2-Chloro-5-fluoropyrimidine C화학적 특성, 용도, 생산
화학적 성질
Colorless to light yellow liquid용도
2-Chloro-5-fluoropyrimidine is used to prepare 2,4-disubstituted-5-fluoropyrimidine , which is a biologically active molecule seen in anticancer agents like 5-fluorouracil.제조 방법
Synthesis of 2-chloro-5-fluoropyrimidine: add 2,4-Dichloro-5-fluoropyrimidine and reducing metal powder to the solvent, stir to raise the temperature to the reaction temperature, slowly add acid dropwise, and keep the temperature until the reaction is completed Finish. Filtration, phase separation or direct evaporation of the solvent, and distillation under reduced pressure to remove the solvent to obtain 2-chloro-5-fluoropyrimidine.참고 문헌
[1] A. Dunaiskis. “LARGE SCALE SYNTHESIS OF 2-CHLORO-5-FLUOROPYRIMIDINE.” Organic Preparations and Procedures International 27 1 (1995): 600–602.[2] A. DUNAISKIS. “ChemInform Abstract: Large Scale Synthesis of 2-Chloro-5-fluoropyrimidine.” ChemInform 26 52 (1995).
2-Chloro-5-fluoropyrimidine 준비 용품 및 원자재
원자재
준비 용품
2-Chloro-5-fluoropyrimidine 공급 업체
글로벌( 372)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 |
sales@win-winchemical.com | China | 14350 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20293 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9312 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 |
stella@zetchem.com | China | 2136 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 |
act@arborchemical.com | CHINA | 906 | 58 |
Win-Win Chemical CO., Limited | 0086-577-64498589 |
sales@win-winchemical.com | CHINA | 998 | 58 |
2-Chloro-5-fluoropyrimidine 관련 검색:
LAMBDACYHALOTHRIN 테크니컬 플루시토신 클로로디플루오르메탄
5-Fluoropyrimidine
2-Chloropyrimidine
2-CHLORO-5-FLUOROPYRIMIDIN-4-ONE
2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE
4-AMINO-2-CHLORO-5-FLUOROPYRIMIDINE,4-AMINO-2-CHLORO-5-FLUOROPYRIMIDINE GC 95.0%,2-Chloro-5-fluoropyrimidine-4-amine
2,4-Dichloro-5-fluoropyrimidine
3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine
Pyrimidine, 4-chloro-6-fluoro- (9CI)
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
2-Fluoro-3,5-dichloropyridine
4,6-Dichloro-5-fluoropyrimidine
3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride
4-(1-bromoethyl)-6-chloro-5-fluoropyrimidine
CHEMBRDG-BB 4015094