Allopregnanolone

Allopregnanolone 구조식 이미지
카스 번호:
516-54-1
상품명:
Allopregnanolone
동의어(영문):
Brexanolone;ALLOPREGNANOLONE;Anlotinib Dihydrochloride;(3a)-Allopregnanolone;allotetrahydroprogesterone;3α-hydroxy-5α-pregnan-20-one;1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one;5α-P;3α-OH-DHP;3α,5α-THP
CBNumber:
CB5418550
분자식:
C21H34O2
포뮬러 무게:
318.49
MOL 파일:
516-54-1.mol

Allopregnanolone 속성

녹는점
176-178°
알파
D +87.7° (abs alc)
끓는 점
431.2±18.0 °C(Predicted)
밀도
1.053±0.06 g/cm3(Predicted)
저장 조건
Store at RT
용해도
클로로포름: 20 mg/mL, 투명, 무색
산도 계수 (pKa)
15.12±0.70(Predicted)
물리적 상태
흰색 고체
색상
하얀색
Merck
13,272
BRN
3211363
안정성
공급된 상태로 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 1개월 동안 보관할 수 있습니다.
InChIKey
AURFZBICLPNKBZ-SYBPFIFISA-N
CAS 데이터베이스
516-54-1(CAS DataBase Reference)

안전

안전지침서 22-24/25
WGK 독일 3
RTECS 번호 TU4383000
F 고인화성물질 10

Allopregnanolone C화학적 특성, 용도, 생산

개요

Allopregnanolone is an endogenous inhibitory pregnane neurosteroid that is synthesized from progesterone . It acts as a positive allosteric modulator of GABAA receptors at nM concentrations (exhibiting the greatest potentiation at isoforms containing δ subunits) and of GABAC receptors at μM concentrations. Allopregnanolone displays effects similar to other GABAA receptor potentiators such as benzodiazepines, including potent anticonvulsant, anxiolytic, and sedative activity.

용도

(3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain.

생물학적 활성

GABA A receptor positive allosteric modulator. Neuroactive steroid.

Allopregnanolone 준비 용품 및 원자재

원자재

준비 용품


Allopregnanolone 공급 업체

글로벌( 221)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5993 58
shandong perfect biotechnology co.ltd
+86-53169958659; +8618596095638
sales@sdperfect.com China 294 58
Hebei Xinsheng New Material Technology Co., LTD.
+86-16632316109
xinshengkeji@xsmaterial.com China 1100 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9348 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@
sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32480 60
Jinan Chenghui-Shuangda Chemical Co.,Ltd
+86-531-58897082
ericqiao@jnchsd.com CHINA 158 58
Jinan Shengqi pharmaceutical Co,Ltd
86+18663751872
christine@shengqipharm.com CHINA 491 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460
faith@widelychemical.com CHINA 742 58
career henan chemical co
+86-0371-86658258 15093356674;
factory@coreychem.com China 29826 58

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