Alfaxalone
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Alfaxalone 속성
- 녹는점
- 172-174°
- 알파
- D26 +113.4° (c = 1.2 in chloroform).
- 끓는 점
- 409.59°C (rough estimate)
- 밀도
- 1.0834 (rough estimate)
- 굴절률
- 1.5192 (estimate)
- 저장 조건
- Store at RT
- 용해도
- 클로로포름: 5mg/mL, 투명, 무색
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 15.05±0.70(Predicted)
- 색상
- 하얀색
- InChI
- InChI=1/C21H32O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h13-17,19,23H,4-11H2,1-3H3/t13-,14+,15-,16+,17-,19+,20-,21+/s3
- InChIKey
- DUHUCHOQIDJXAT-YYJIQYHHNA-N
- SMILES
- [C@]12([H])C(=O)C[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CC[C@@]1([H])C[C@H](O)CC[C@]21C)C(=O)C |&1:0,5,7,10,12,16,19,23,r|
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
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위험 카페고리 넘버 | 22 | ||
안전지침서 | 22-36 | ||
유엔번호(UN No.) | UN 2811 6.1/PG 3 | ||
WGK 독일 | 3 | ||
RTECS 번호 | TU4157800 | ||
독성 | LD50 i.v. in mice: 43 mg/kg (Al-Khawashki) |
그림문자(GHS): | |||||||||||||||
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신호 어: | Danger | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Alfaxalone C화학적 특성, 용도, 생산
용도
Anesthetic;nociception blocker생물학적 활성
A neurosteroid anesthetic that directly activates and potentiates GABA A receptor-activated membrane current (I GABA ). Efficacy but not potency is determined by the alpha subunit of the receptor (EC 50 values are 1.4, 1.8, 2.1, 2.4 and 2.5 μ M for α 1 β 1 γ 3, α 1 β 1 γ 1, β 1 γ 1, α 2 β 1 γ 2L and α 1 β 1 γ 2L isoforms respectively).Mechanism of action
Alfaxalone's mechanism of action is chloride ion modulation associated with interaction with the neuronal membrane GABA A receptor[1].Alfaxalone 준비 용품 및 원자재
원자재
준비 용품
Alfaxalone 공급 업체
글로벌( 62)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Hunan Yuanye Pharmaceutical Co., Ltd. | +8615857615745 |
2675013845@qq.com | China | 87 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 1143 | 58 |
Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 +86-15850508050 |
sean.lv@synzest.com | China | 323 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 |
Ethan@dornechem.com | China | 3138 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 24099 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15394 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
PT CHEM GROUP LIMITED | |
peter68@ptchemgroup.com | China | 35426 | 58 |
Xuzhou B&C Chemical Co.,Ltd | +86-400-0516-021 |
info@bcpharma.com | China | 1913 | 58 |
Alfaxalone 관련 검색:
AGOMELATINE
Alfaxalone Alfadolone Mixture
Δ16-Alfaxalone
5-ALPHA-PREGNAN-3-ALPHA, 17,21-TRIOL-11,20-DIONE 3-ACETATE
Alfaxalone
5-ALPHA-PREGNAN-3-BETA, 17,21-TRIOL-11,20-DIONE
3alpha,21-dihydroxy-5alpha-pregnane-11,20-dione 21-acetate
5-ALPHA-PREGNAN-3-ALPHA, 17,21-TRIOL-11,20-DIONE 3,21-DIACETATE
ALFAXALONE ACETATE
Alphadolone
5-ALPHA-PREGNAN-3-ALPHA, 17-DIOL-11,20-DIONE
5-ALPHA-PREGNAN-3-ALPHA, 17,21-TRIOL-11,20-DIONE 21-ACETATE