RHOEADINE
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RHOEADINE 속성
- 녹는점
- 222°C
- 알파
- D23 +235° (c = 1.01 in chloroform); D22 +174° (c = 0.69 in pyridine)
- 끓는 점
- 510.32°C (rough estimate)
- 밀도
- 1.3202 (rough estimate)
- 굴절률
- 1.5614 (estimate)
- 산도 계수 (pKa)
- 6.40±0.40(Predicted)
- 수용성
- 832.6mg/L(25℃)
- LogP
- 3.920 (est)
안전
RHOEADINE C화학적 특성, 용도, 생산
개요
This alkaloid was found by Hesse in Papaver rhoeas Linn (red poppy) and its reputed existence in opium now appears doubtful. The base crystallizes from a mixture of CHCl3 and Et20 and sublimes at 21 5-225°C/0.02 mm. It has [α]17.5D + 232° (CHCI 3) or [α]19D + 243° (CHCl3). It behaves as a weak base and is sparingly soluble in H20, alkaline solutions and most organic solvents. It dissolves in mineral acids giving an intensely red solution but investigation shows that only a small proportion of the alkaloid is used to produce the colour, the major part being converted into a colourless, crystalline substance, Rhoeagenine, a much stronger base, non-volatile, and stable to acids. This base is not isomeric with the alkaloid as first thought but has the formula C2oH1906N, m.p. 236-8°C; [α]19D + l68° (AcOH).).Rhoeadine itself contains two methylenedioxy groups, one methoxy group and an N-methyl group. The salts are not easy to prepare but a crystalline hydriodide dihydrate is formed by addition of KI to a solution of the alkaloid in AcOH. The ultraviolet spectrum of the alkaloid shows absorption maxima at 205, 240 and 292 mμ.
용도
As an isoquinoline alkaloid, Rhoeadine can be used in the therapeutic field particularly for the prevention and the treatment of pathologies implying a central and/or peripheral disorder.참고 문헌
Hesse., Annalen, Suppl., 4, 50 (1S65)Hesse., ibid, 140, 145 (1S66)
Spath., Monatsh., 68,33 (1936)
Awe., Arch. Pharm., 279,116 (1941)
Santavy etat., Collect. Czech. Chem. Commun., 30,335,3479 (1965)
Mass spectrum:
Dolejs, Hanus., Tetrahedron, 23, 2997 (1967)
Stereochemistry:
Shamma et at., Chem. Commun., 212 (1968)
RHOEADINE 준비 용품 및 원자재
원자재
준비 용품
RHOEADINE 공급 업체
글로벌( 29)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 |
market03@meryer.com | China | 40241 | 62 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15421 | 60 |
Shanghai Tauto Biotech Co., Ltd. | 021-51320588 |
tauto@tautobiotech.com | China | 3989 | 66 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 |
3008007409@qq.com | China | 27322 | 60 |
Shanghai Jizhi Biochemical Technology Co. Ltd. | 400-400-400-9004166 18616739031 |
3007523370@qq.com | China | 52712 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 55717 | 58 |
RHOEADINE 관련 검색:
Isochroman
2-(Benzo[d][1,3]dioxol-5-yl)ethanol
Phenylephrine
INETERMEDIATE OF GALANTHAMINE 1
(R)-(-)-1-AMINO-1-PHENYL-2-METHOXYETHANE
4-CHLORO-2-FLUOROBENZYLAMINE HYDROCHLORIDE
dioxethedrin
(R)-4-(1-Aminoethyl)phenol (S)-hydroxybutanedioate salt
1-(4-METHOXY-PHENYL)-2-METHYLAMINO-ETHANOL
Norepinephrine
RHOEADINE
etafedrine
Synephrine
(S)-(-)-1-(4-Methoxyphenyl)ethylamine
1-(1,3-BENZODIOXOL-5-YL)PROPAN-2-AMINE
1-(1,3-benzodioxol-5-yl)propan-1-amine
(1R,2R)-(+)-2-AMINO-1,2-DIPHENYLETHANOL
2,2'-DIMETHYLBIBENZYL