PP2A1
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PP2A1 속성
- 저장 조건
- -70°C
안전
안전지침서 | 23-24/25 | ||
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WGK 독일 | 1 |
PP2A1 C화학적 특성, 용도, 생산
용도
Protein phosphatase 2A1 has been used to treat human fibroblast cells prior to western blot analysis.일반 설명
Protein Phosphatase 2A1 (PP2A1) belongs to the PP2A family and comprises trimeric A, B and C subunits. PPA2 enzymes are serine/threonine phosphatases and exist as several isoforms.Biochem/physiol Actions
Protein Phosphatase 2A is a cytoplasmic protein, which colocalizes with microtubule proteins and is involved in the dephosphorylation of the tau protein and oncoprotein 18. Protein Phosphatase 2A1 (PP2A1) binds to polymerized microtubule proteins and may be targeted by tubulin in modulating phosphatase activity. PP2A1 is implicated as a growth suppressor and is associated with dysregulation in cancer. It also regulates cell cycle, RNA splicing differentiation, and signal transduction. PP2A dysfunction is correlated to the tau protein deregulation in Alzheimer′s disease pathophysiology. Protein Phosphatase 2A1 is a divalent cation-dependent protein serine/threonine phosphatase implicated as a growth suppressor and is associated with dysregulation in cancer.PP2A1 준비 용품 및 원자재
원자재
준비 용품
PP2A1 공급 업체
글로벌( 7)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Riedel-de Haen AG | -- |
United States | 6825 | 87 | |
SIGMA-RBI | -- |
Switzerland | 6913 | 91 | |
EMD Biosciences, Inc. | -- |
technical@calbiochem.com | United States | 6529 | 66 |
VWR International | -- |
solutions@vwr.com | United Kingdom | 6554 | 82 |
Nacalai Tesque, Inc. | -- |
info-tech@nacalai.co.jp | Japan | 6048 | 75 |
BIOMOL INTERNATIONAL, LP | -- |
info@biomol.com | United States | 1503 | 77 |
Upstate | -- |
info@upstate.com | United States | 876 | 76 |