2-((4-methoxynaphthalen-2-yl)amino)-5-nitrobenzoic acid
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2-((4-methoxynaphthalen-2-yl)amino)-5-nitrobenzoic acid 속성
- 끓는 점
- 553.1±50.0 °C(Predicted)
- 밀도
- 1.421±0.06 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml; Ethanol: slightly soluble
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 2.26±0.22(Predicted)
안전
2-((4-methoxynaphthalen-2-yl)amino)-5-nitrobenzoic acid C화학적 특성, 용도, 생산
개요
MONNA is a selective inhibitor of anoctamin-1 (ANO1; IC50 = 0.08 μM in Xenopus oocytes), a calcium-activated chloride channel (CaCC). It is selective for ANO1 over the chloride channels bestrophin-1, chloride channel protein 2, and cystic fibrosis transmembrane conductance regulator up to 10 μM. MONNA (10 μM) induces full vasorelaxation of preconstricted mouse isolated mesenteric arteries in the presence or absence of chloride. It also hyperpolarizes isolated rat mesenteric arteries under resting conditions.용도
2-[(4-Methoxy-2-naphthalenyl)amino]-5-nitrobenzoic Acid selectively inhibits the calcium-activated chloride channel, anoctamin-1. 2-[(4-Methoxy-2-naphthalenyl)amino]-5-nitrobenzoic Acid has potential applications for developing treatments for hypertension, cystic fibrosis, bronchitis, asthma, and hyperalgesia.2-((4-methoxynaphthalen-2-yl)amino)-5-nitrobenzoic acid 준비 용품 및 원자재
원자재
준비 용품
2-((4-methoxynaphthalen-2-yl)amino)-5-nitrobenzoic acid 공급 업체
글로벌( 33)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 |
757984502@qq.com | China | 892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131981 | 58 |
| ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 |
sales@zhiwe.net | China | 578 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 |
info@chemlin.com.cn | China | 17989 | 64 |
| AN PharmaTech Co Ltd | 86(21)68097365 |
sales@anpharma.net | China | 4901 | 55 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 |
sales@pharmacodia.com | China | 2317 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |