2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID C화학적 특성, 용도, 생산
개요
N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of Δ9-tetrahydrocannabinol (Δ9-THC).
정의
ChEBI: A fatty acid-taurine conjugate derived from arachidonic acid.
2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID 준비 용품 및 원자재
원자재
준비 용품
2-[(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)AMINO]-ETHANE SULFONIC ACID 공급 업체
