ChemicalBook >제품 카탈로그 >생화학 공학>억제제>세포 골격 신호>HSP 예 : HSP90 억제제>CH5138303

CH5138303

CH5138303 구조식 이미지

카스 번호:: 959763-06-5

상품명:: CH5138303

동의어(영문):: CH5138303;CH5138303cas;CH5138303_Hsp90;CH5138303 USP/EP/BP;4-[[4-Amino-6-(5-chloro-1H,3H-naphtho[1,8-cd]pyran-6-yl)-1,3,5-triazin-2-yl]thio]butanamide;4-[4-amino-6-(5-chloro-1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazin-2-ylsulfanyl]butanamide;4-((4-Amino-6-(5-chloro-1,3-dihydrobenzo[de]isochromen-6-yl)-1,3,5-triazin-2-yl)thio)butanamid;Butanamide, 4-[[4-amino-6-(5-chloro-1H,3H-naphtho[1,8-cd]pyran-6-yl)-1,3,5-triazin-2-yl]thio]-;4-[(4-Amino-6-[7-chloro-3-oxatricyclo[7.3.1.0(5,13)] trideca-1(13),5,7,9,11-pentaen-8-yl]-1,3,5-triazin-2-yl)sulfanyl]butanamide

CBNumber:: CB72706190

분자식:: C19H18ClN5O2S

포뮬러 무게:: 415.9

MOL 파일:: 959763-06-5.mol

속성

안전

용도

공급 업체 52

CH5138303 속성

끓는 점: 813.1±75.0 °C(Predicted)

밀도: 1.51±0.1 g/cm3(Predicted)

저장 조건: Desiccate at -20°C

용해도: insoluble in H2O; insoluble in EtOH; ≥19.95 mg/mL in DMSO

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 16.39±0.40(Predicted)

안전

CH5138303 C화학적 특성, 용도, 생산

개요

CH5138303 is a triazine Hsp90 inhibitor. CH5138303 binds to the N-terminus of Hsp90α (K_d = 0.52 nM) and inhibits growth of HCT116 and NCI-N87 human tumor cell lines in vitro (IC₅₀s = 89 and 66 nM, respectively). CH5138303 also inhibits growth of human NCI-N87 gastric cancer xenografts (ED₅₀ = 3.9 mg/kg) and displays high oral bioavailability in mice.

CH5138303 준비 용품 및 원자재

원자재

준비 용품

CH5138303 공급 업체

글로벌( 52)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29016	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4428	55

CH5138303 관련 검색:

BIIB-021 Panobinostat 5-[2,4-Dihydroxy-6-(4-nitrophenoxy)phenyl]-N-(1-methyl-4-piperidinyl)-3-isoxazolecarboxamide NVP-HSP990(HSP990) Luminespib 17-AAG