(S)-PFI-2 (hydrochloride)
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(S)-PFI-2 (hydrochloride) 속성
- 저장 조건
- 2-8°C
- 용해도
- ≤0.5mg/ml in ethanol;2mg/ml in DMSO;5mg/ml in dimethyl formamide
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
(S)-PFI-2 (hydrochloride) C화학적 특성, 용도, 생산
용도
(S)-PFI-2 is n analog of (R)-PFI-2 a potent and selective lysine methyltransferase SETD7 inhibitor which is a crucial factor in many disease related pathways.일반 설명
(S)-PFI-2 is a negative control enantiomer and a biotinylated derivative of (R)-PFI-2, which helps to study the biological activity of SETD7 (SET domain containing (lysine methyltransferase) 7).Biochem/physiol Actions
(S)-PFI-2 is the negative control probe for (R)-PFI-2 hydrochloride, which is a histone-lysine N-methyltransferase (HKMT) inhibitor selective for SETD7 (SET9). (R)-PFI-2 has 1000-fold selectivity for SETD7 (SET9) over other methyltransferases and other non-epigenetic targets and an IC50 value of 2 nM. (S)-PFI-2 is 500-fold less active. For characterization details of (R)-PFI-2 and (S)-PFI-2, please visit the PFI-2 probe summary on the Structural Genomics Consortium (SGC) website.(R)-PFI-2, the active SETD7 probe, is available from Sigma. To learn more about and purchase (R)-PFI-2, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc(S)-PFI-2 (hydrochloride) 준비 용품 및 원자재
원자재
준비 용품
(S)-PFI-2 (hydrochloride) 공급 업체
글로벌( 25)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9414 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 |
chenjw@absin.cn | China | 24734 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44894 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 |
sales@chemhifuture.com | China | 4030 | 58 |