POMALIDOMIDE-C9-CO2H
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POMALIDOMIDE-C9-CO2H 속성
- 끓는 점
- 714.1±55.0 °C(Predicted)
- 밀도
- 1.326±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 물리적 상태
- 분말 또는 결정
- 산도 계수 (pKa)
- 4.78±0.10(Predicted)
안전
POMALIDOMIDE-C9-CO2H C화학적 특성, 용도, 생산
용도
Protein degrader builiding block Pomalidomide-C9-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and an alkyl-chain crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.POMALIDOMIDE-C9-CO2H 준비 용품 및 원자재
원자재
준비 용품
POMALIDOMIDE-C9-CO2H 공급 업체
글로벌( 18)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 |
1924344760@confluore.cn | China | 2996 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 |
han_yajun@dctc.daicel.com | China | 7183 | 65 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 |
info@SuperLan-chem.com | China | 9945 | 58 |
Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 |
1924344760@qq.com | China | 4824 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 |
1927928688@qq.com | China | 1385 | 58 |
POMALIDOMIDE-C9-CO2H 관련 검색:
E3 ligase Ligand-Linker Conjugates 49
6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid
E3 ligase Ligand-Linker Conjugates 55
1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
Pomalidomide-6-2-2-6-N3
Pomalidomide-amido-C1-Br
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide
Pomalidomide-C6-PEG3-butyl iodide
4-[(8-Aminooctyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
Pomalidomide-C3-NH2
Pomalidomide-C6-NH2?hydrochloride
Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-