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(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile 구조식 이미지

카스 번호:: 38321-02-7

상품명:: (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile

동의어(영문):: d-Verapamil;Dexverapami;Dexverapamil;Dexverapamil Hydrochloride;[R,(+)]-2-(3,4-Dimethoxyphenyl)-2-isopropyl-5-(N-methyl-3,4-dimethoxyphenethylamino)valeronitrile;(R)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile;(aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile;(αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile;Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (R)-;Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-, (αR)-

CBNumber:: CB7941337

분자식:: C27H38N2O4

포뮬러 무게:: 454.61

MOL 파일:: 38321-02-7.mol

속성

안전

용도

공급 업체 11

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile 속성

녹는점: 129-131°C

끓는 점: 586.1±50.0 °C(Predicted)

밀도: 1.058±0.06 g/cm3(Predicted)

산도 계수 (pKa): 8.97±0.50(Predicted)

안전

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile C화학적 특성, 용도, 생산

화학적 성질

Off-White Solid

용도

Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells

정의

ChEBI: A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby p tentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil.

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile 준비 용품 및 원자재

원자재

준비 용품

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile 공급 업체

글로벌( 11)공급 업체

공급자	전화	이메일	국가	제품 수	이점
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2127	70
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9685	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
QUALITY CONTROL SOLUTIONS LTD.	13670046396	ORDERS@QCSRM.COM	China	18810	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58

(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile 관련 검색:

페닐아세토나이트릴 베라파밀 하이드로클로라이드 2-(4-Methoxyphenyl)-2-methylpropanenitrile Devapamil 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile METHOXY-(-)-VERAPAMIL HYDROCHLORIDE R(+)-VERAPAMIL HYDROCHLORIDE Valeronitrile Verapamil (3,4-Dimethoxyphenyl)acetonitrile (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile 4-HYDROXY-3-METHOXYPHENYLACETONITRILE NORVERAPAMIL Emopamil P-O-DESMETHYL VERAPAMIL 1-(3,4-DIMETHOXYPHENYL)-VALERONITRILE 2-(3,4-DIMETHOXY-PHENYL)-5-{[2-(3,4-DIMETHOXYPHENYL)-ETHYL]METHYL-AMINO}-PENTANENITRILE 2-(3-METHOXYPHENYL)-2-METHYLPROPANENITRILE