Pal-Tripeptide-1

Pal-Tripeptide-1 구조식 이미지
카스 번호:
147732-56-7
상품명:
Pal-Tripeptide-1
동의어(영문):
Pal-AHK;L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-;Pal-GHK-OH;Collaxyl II;Palmitoyl-GHK;Pal-GHK, >=95%;Pal-Tripeptide-1;Palm-Gly-His-Lys;Peptides PAL-Ghk;PAL-GLY-HIS-LYS-OH
CBNumber:
CB81214020
분자식:
C30H54N6O5
포뮬러 무게:
578.79
MOL 파일:
147732-56-7.mol

Pal-Tripeptide-1 속성

끓는 점
913.0±65.0 °C(Predicted)
밀도
1.105
저장 조건
Store at -20°C
용해도
DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 30 mg/ml
물리적 상태
고체
산도 계수 (pKa)
3.16±0.10(Predicted)
시퀀스
Pal-Gly-His-Lys
InChIKey
BYUQATUKPXLFLZ-UIOOFZCWSA-N
SMILES
C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CNC(=O)CCCCCCCCCCCCCCC
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

Pal-Tripeptide-1 C화학적 특성, 용도, 생산

개요

A peptide is two or more amino acids joined together and is the building block of protein. Peptides fall into three main categories: signal peptides, carrier peptides, and those that inhibit nerve signals. Signal peptides, like palmitoyl tripeptide-1, act as messengers to cells, which trigger collagen synthesis, which then increases skin firmness.Palmitoyl tripeptide-1 is a small three amino acid signal peptide with the amino sequence of glycine-histidine-lysine (GHK). GHK is attached to palmitic acid (a fatty acid) to increase its skin penetration and oil solubility.

용도

Palmitoyl Tripeptide-1, has shown to have effects on on collagen, fibronectin, hyaluronic acid synthesis in human dermal fibroblasts, and thus can be used in preparation of antiaging cosmetic creams.

주요 응용

Palmitoyl Tripeptide-1 (Pal-GHK, SpecPed? PT1P) is useful in anti-aging products and wrinkle treatment products such as gels, serums, lotions and creams. Acting as messengers of cutaneous restructuration and repair, this peptide works synergistically to restore and maintain the skin's youthful appearance.

Clinical Use

Applying palmitoyl tripeptide-1 directly to your skin tells the cells to make more collagen, stimulating new collagen production. It requires at least one month or more to begin to see visible changes from new collagen with maximum results visible after 3 to 4 months. Erin Gilbert, MD, FAAD, Ph.D., and board-certified dermatologist and neuroscientist, continues: "Peptides can be included in serums, moisturizers, and masks," Gilbert explains. "They are also included in some topical serums used after micro-needling or superficial laser procedures to increase the penetration of the peptide and help the skin recover from the procedure."

Safety

The CIR Expert Panel concluded that peptides, such as palmitoyl tripeptide-1, are safe in cosmetics and self-care products. Environmental Working Group (EWG) currently scores palmitoyl tripeptide-1 as “1” or “low hazard.”Overall, peptides, such as palmitoyl tripeptide-1, mimic what already exists in the human body and research on peptides’ impact on the skin shows limited to no skin irritation. In terms of toxicity caused by peptides, there is no published research to document any known toxicity.

Pal-Tripeptide-1 준비 용품 및 원자재

원자재

준비 용품


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