LAUROLITSINE

LAUROLITSINE 구조식 이미지
카스 번호:
5890-18-6
상품명:
LAUROLITSINE
동의어(영문):
Norboldine;Aids161652;Norpoldine;Aids-161652;Laurolistine;Laurolitsine;Norisoboidine;norisopoldine;(+)-Norboldine;Tramadol Impurity 22-d6
CBNumber:
CB91091507
분자식:
C18H19NO4
포뮬러 무게:
313.35
MOL 파일:
5890-18-6.mol

LAUROLITSINE 속성

녹는점
138-140 ºC
끓는 점
453.15°C (rough estimate)
밀도
1.313
굴절률
1.5100 (estimate)
용해도
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
물리적 상태
Cryst.
산도 계수 (pKa)
9.81±0.20(Predicted)
색상
Off-white to pink

안전

LAUROLITSINE C화학적 특성, 용도, 생산

개요

This noraporphiae alkaloid has been obtained from Litsea japonica and Neolitsea sericea and swells at 11 5-8°C before melting. It is dextrorotatory with [o:lbl + 102.5° (EtOH) and yields a picrate as yellow needles, m.p. 212°C (dec.) and a picrolonate, m.p. 239°C (dec.). The N-methyl derivative is identical with boldine.

용도

Laurolitsine is an alkaloid extracted from Polyalthia longifolia var. pendula.

정의

ChEBI: An isoquinoline alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV 1 integrase.

참고 문헌

Nakasato, Nomura., Chem. Pharm. Bull., (Tokyo), 7, 780 (1959)
Kozuka., J. Ph arm. Soc., Japan, 82, 1567 (1962)
See also:
Johns, Lamberton., Austral. J. Chem., 20, 1277 (1967)

LAUROLITSINE 준비 용품 및 원자재

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준비 용품


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