Phenactropinium chloride

Phenactropinium chloride 구조식 이미지
카스 번호:
3784-89-2
상품명:
Phenactropinium chloride
동의어(영문):
Phenactropinium;Phenactropinium chloride;3-[Hydroxy(phenyl)acetoxy]-8-methyl-8-(2-oxo-2-phenylethyl)-8-azoniabicyclo[3.2.1]octane;(8-methyl-8-phenacyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate chloride;(8-methyl-8-phenacyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-ethanoate chloride;2-hydroxy-2-phenyl-acetic acid (8-methyl-8-phenacyl-8-azoniabicyclo[3.2.1]octan-3-yl) ester chloride
CBNumber:
CB91116431
분자식:
C24H28ClNO4
포뮬러 무게:
0
MOL 파일:
3784-89-2.mol

Phenactropinium chloride 속성

녹는점
195-197°

안전

Phenactropinium chloride C화학적 특성, 용도, 생산

Originator

Trophenium ,American Cyanamid (AHP), US ,1961

Manufacturing Process

330 g (1.2 M) of homatropine were dissolved in 1 liter of dry methyl ethyl ketone and gently refluxed on a water-bath during the gradual addition of a solution of 204 g (1.32 M) redistilled phenacyl chloride in 200 ml of the same solvent. After 10 to 15 minutes 1 g of previously prepared homatropine phenacyl chloride was added to avoid formation of a supersaturated solution of the quaternary compound. Reflux was continued for 9 hours, then the thick suspension was allowed to cool, filtered and washed with 200 ml methyl ethyl ketone to yield 490 g (95%) slightly creamy solid, MP 188°C to 191°C.
For purification the crude quaternary salt was dissolved in hot ethyl alcohol (2 ml/g) and warm dry acetone (8 ml/g) was stirred into the clear filtrate. On cooling, 387 g (78 % recovery) of a pure white powder, MP 195°C to 197°C, were obtained, in which the ionizable chlorine assayed at 99.7% of the theoretical value.

Therapeutic Function

Antihypertensive

Phenactropinium chloride 준비 용품 및 원자재

원자재

준비 용품


Phenactropinium chloride 공급 업체

글로벌( 4)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Leancare Ltd. --
enquiry@leancare.co.uk United Kingdom 6460 42
Lanospharma Laboratories Co.,Ltd --
sales@lanospharma.com China 6343 56
2A PharmaChem USA --
sales@2apharmachem.com United States 6148 39
3B Scientific Corporation --
sales@3bsc.com United States 6744 47

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