Quininib
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Quininib 속성
- 저장 조건
- Store at -20°C
- 용해도
- DMSO: 용해될 수 있다
- 물리적 상태
- 결정성 고체
안전
Quininib C화학적 특성, 용도, 생산
개요
Quininib is an antagonist of the cysteinyl leukotriene 1 (CysLT1) and CysLT2 receptors (IC50s = 1.4 and 52 μM, respectively). It inhibits tubule formation in HMEC-1 cells when used at concentrations of 3.16 and 10 μM and inhibits sprout formation in isolated mouse aortic rings in an ex vivo model of angiogenesis when used at 10 μM. Quininib (3 μM) decreases angiogenesis in an oxygen-induced retinopathy mouse model of ocular angiogenesis, preventing revascularization when used at concentrations of 0.5 and 3 μM, as well as increasing neovascularization and vascular density when used at 3 μM. It reduces tumor growth and inhibits angiogenesis in an HT-29 colorectal cancer mouse xenograft model when administered at a dose of 50 mg/kg every three days.용도
Quininib is a novel regulator of Ocular Angiogenesis, significantly inhibiting angiogenic tubule formation in HMEC-1 cells, angiogenic sprouting in aortic ring explants and retinal revascularisation in OIR mice.Quininib 준비 용품 및 원자재
원자재
준비 용품
Quininib 공급 업체
글로벌( 19)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32024 | 58 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4428 | 55 |
ShangHai Angti Biotechnology Co., Ltd. | 13764913901 |
info@angtibio.com | China | 4989 | 55 |
ATK CHEMICAL COMPANY LIMITED | 3429815786 13301662590 |
sales@atkchemical.com | China | 9993 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6777 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11217 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8140 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing@energy-chemical.com | China | 44918 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8617 | 58 |