Gemfibrozil
Gemfibrozil
- CAS:
- 25812-30-0
- MF:
- C15H22O3
- MW:
- 250.33
Suppliers by country/region
- India(47)
- China(206)
- United States(62)
- Russia(1)
- Canada(10)
- United Kingdom(17)
- Germany(11)
- Europe(3)
- Switzerland(4)
- France(4)
- South Korea(2)
- Italy(2)
- Indonesia(1)
- Brazil(5)
- Israel(2)
- Belgium(2)
- The Netherlands(2)
- Venezuela(1)
- Spain(1)
- Poland(1)
- Jordan(1)
- Greece(1)
- United Arab Emirates(1)
- Cyprus(1)
- Malaysia(1)
- Nepal(1)
Company Type
Properties
- Melting point:
- 61-63°C
- Boiling point:
- 158-159 C
- Density
- 1.1109 (rough estimate)
- refractive index
- 1.5020 (estimate)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
- form
- powder
- pka
- 4.75±0.45(Predicted)
- color
- White to Off-White
- Water Solubility
- >0.5g/L(temperature not stated)
- Merck
- 14,4388
- BCS Class
- 2
- CAS DataBase Reference
- 25812-30-0(CAS DataBase Reference)
- IARC
- 3 (Vol. 66) 1996
- EPA Substance Registry System
- Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-63-62-46-36/38-21
- Safety Statements
- 36-53-36/37-26-25
- WGK Germany
- 3
- RTECS
- YV7120000
- HazardClass
- IRRITANT
- HS Code
- 2918992090
- Hazardous Substances Data
- 25812-30-0(Hazardous Substances Data)
- Toxicity
- LD50 in mice, rats (mg/kg): 3162, 4786 orally (Kurtz)
Use
Gemfibrozil, 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid (Lopid), is a congener of clofibratethat was used first in the treatment of hyperlipoproteinemia inthe mid-1970s. Its mechanism of action and use are similar tothose of clofibrate. Gemfibrozil reduces plasma levels ofVLDL triglycerides and stimulates clearance of VLDL fromplasma. The drug has little effect on cholesterol plasma levelsbut does cause an increase of HDL.Gemfibrozil is absorbed quickly from the gut and excretedunchanged in the urine. The drug has a plasma half-life of1.5 hours, but reduction of plasma VLDL concentration takesbetween 2 and 5 days to become evident. The peak effect of its hypolipidemic action may take up to 4 weeks to becomemanifest.
47 India supplier list of "Gemfibrozil"
- Product Name:Gemfibrozil
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Ahmedabad,INDIA
- Product Name:Gemfibrozil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Gemfibrozil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:GEMFIBROZIL 70% DC GRANULES
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Gemfibrozil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Gemfibrozil
- Products Intro:Brand:sigma aldrich | Product Number:91823 | Purity:analyticalstandard
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Gemfibrozil >98% (GC), powder
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.070839
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Gemfibrozil
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Gemfibrozil
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Gemcitabine Intermediates
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA