Calicheamicin suppliers
Calicheamicin
- CAS:
- 108212-75-5
- MF:
- C55H74IN3O21S4
- MW:
- 1368.34
Suppliers by country/region
Company Type
Properties
- alpha
- D26 -124° (c = 0.98%, EtOH)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 100 mg/mL (73.08 mM);Water : < 0.1 mg/mL (insoluble)
- pka
- 7.13±0.60(Predicted)
Safety Information
Use
Calicheamicin, also known as Calicheamicin gamma(1,I) or Calichemicin gamma1, is an potent enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora. Calicheamicin targets DNA and cause strand scission. Calicheamicin binds with DNA in the minor groove, wherein it then undergos a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1,4-didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA, which ultimately leads to strand scission. The specificity of binding of calicheamicin to the minor groove of DNA is due to the aryltetrasaccharide group of the molecule.
95 supplier list of "Calicheamicin "
- Product Name:Calicheamicin
- Products Intro:Purity: 99% | Package: 1kg; 25kg; or larger package as required
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Specialty chemicals,OLED materials,Custom synthesis service
$8.00-1.00 / 1kg
- Product Name:Calicheamicin gamma1
- Products Intro:Purity: 99% | Package: 1kg;8USD|25kg;5USD|100kg;1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
- Product Name:calicheamicin gamma(1)I
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Calicheamicin
- Products Intro:Purity: >=95% by HPLC | Package: 1mg | CustNote: BOC Sciences also provides custom synthesis services for Calicheamicin.
- Company Type: Trader
- Country/Region: UNITED STATES
$7.00/ 1KG
- Product Name: calicheamicin gamma(1)I
- Products Intro:Purity: 99% | Package: 1KG;7USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Calicheamicin
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Specialty chemical,UV Curing & Brightener,OLED Chemicals,CDMO SERVICES
- Product Name:Calicheamicin
- Products Intro:Purity: 0.99 | Package: 5KG;1KG | CustNote: Factory direct sales
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate
- Product Name:calicheamicin gamma(1)I
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:calicheamicin gamma(1)I USP/EP/BP
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CALICHEAMICIN
- Products Intro:Purity: 98%+ | Package: Standard or custom package | CustNote: excellent quality and reliable supplier
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes