fluocinolone16,17-acetonide manufacturers and suppliers

fluocinolone16,17-acetonide suppliers

Properties

Melting point:: 267-269 °C(lit.)

alpha: D +95° (chloroform)

Boiling point:: 578.5±50.0 °C(Predicted)

Density: 1.1826 (estimate)

refractive index: 103 ° (C=1, MeOH)

storage temp.: Refrigerator

solubility: Practically insoluble in water, soluble in acetone and in ethanol

pka: 12.78±0.70(Predicted)

color: White to Off-White

Water Solubility: Soluble in water (partly), DMSO, alcohol, chloroform and methanol.

Merck: 14,4150

InChIKey: FEBLZLNTKCEFIT-VSXGLTOVSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes: Xi,Xn

Risk Statements: 36/37/38-40-20/21/22

Safety Statements: 26-36-22

WGK Germany: 3

RTECS: TU3830000

HS Code: 2937220000

Toxicity: LD50 oral in rat: > 4gm/kg

Use

Fluocinolone acetonide,6α,9-difluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, also known as6α-fluorotriamcinolone acetonide, is the 21-acetate derivativeof fluocinolone acetonide and is about 5 times morepotent than fluocinolone acetonide in at least one topicalactivity assay.

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