AT9283 suppliers
AT9283
- CAS:
- 896466-04-9
- MF:
- C19H23N7O2
- MW:
- 381.43
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Properties
- Density
- 1.45
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- insoluble in H2O; ≥19.05 mg/mL in DMSO; ≥47.6 mg/mL in EtOH with ultrasonic
- form
- solid
- pka
- 10.58±0.10(Predicted)
Safety Information
Use
AT-9283 is a broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50s = 3, 3, 1.2, 1.1, and 4 nM, respectively). It also potently (IC50 = <1 μM) inhibits many other kinases, including serine/threonine kinases as well as receptor and non-receptor tyrosine kinases. As Aurora kinases have roles in mitosis, inhibitors of these kinases, including AT-9283, have potential in cancer therapy. Consistent with this, AT-9283 is effective in preventing proliferation of cancer cells both in vitro and in vivo and this effect may be enhanced by combination therapy with other chemotherapeutics.[Cayman Chemical]
94 supplier list of "AT9283"
- Product Name:1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea AT9283
- Products Intro:Purity: 99% | Package: 1kg,5kg,25kg,50kg,200kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Tris (hydroxymethyl) aminoethane,9-phenylcarbazole,2-Methylimidazole,Trifluoromethanesulfonic acid,1-Adamantanecarboxylic acid
- Product Name:AT9283
- Products Intro:Purity: 98% | Package: 1KG;10KG;100KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 5-Heptylresorcinol,Methyl 2-heptyl-4,6-dihydroxybenzoate,Cannabinoids Precursors,2,4-dihydroxy-6-propyl-benzoic acid methyl ester,Benzoic acid, 2-hexyl-4,6-dihydroxy-, methyl ester
You can find AT9283 suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the Germany here.
Browse to the tetrahydrofuran product information displayed by the supplier,
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