BETA-AMANITIN manufacturers and suppliers

BETA-AMANITIN suppliers

BETA-AMANITIN

CAS:: 21150-22-1

MF:: C39H53N9O15S

MW:: 919.95

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Properties

Melting point:: 300°

Boiling point:: 1599.6±65.0 °C(Predicted)

Density: 1.1725 (rough estimate)

refractive index: 1.7400 (estimate)

storage temp.: −20°C

solubility: Water: 1 mg/ml

pka: 4.02±0.10(Predicted)

form: White to off-white powder.

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H300+H310+H330

Precautionary statements: P260-P262-P264-P280-P302+P352+P310-P304+P340+P310

Hazard Codes: T+

Risk Statements: 26/27/28

Safety Statements: 7-28-36/37/39-45

RIDADR: UN 3462 6.1/PG 1

WGK Germany: 3

RTECS: NJ8324000

HazardClass: 6.1(a)

PackingGroup: I

HS Code: 2934999090

Toxicity: LD50 i.p. in albino mice: 0.4 mg/kg (Wieland, Wieland)

Use

β-Amanitin is a cyclic peptide found in several species of the Amanita genus, as well as other poisonous fungi. It inhibits RNA polymerase II and III but not RNA polymerase I or bacterial RNA polymerase, thus preventing mammalian protein synthesis. The biological activity of this toxin is similar to that of α-amanitin but differs structurally by the presence of a carboxyl group, which is useful for coupling reactions.

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