F-AMidine suppliers
F-AMidine
- CAS:
- 877617-45-3
- MF:
- C14H19FN4O2
- MW:
- 294.32
Suppliers by country/region
Properties
- Density
- 1.27±0.1 g/cm3(Predicted)
- pka
- 13.26±0.46(Predicted)
Safety Information
Use
An inhibitor of Peptidyl arginine deiminase 4 (PAD4) activity with an IC50 value of 21.6 μM in an in vitro activity assay. It irreversibly inactivates (kinact/KI = 3,000 M-1min-1) PAD4 by covalently modifying an active site cysteine that is important for its catalytic activity. Dysregulated PAD4 activity has been implicated in cancer and rheumatoid arthritis. F-amidine also inhibits PAD1 and PAD3 with IC50 values of 29.5 and 350 μM, respectively. F-amidine is cytotoxic to HL-60, MCF7 and HT-29 cancer cell lines (IC50s = 0.5, 0.5 and 1 μM, respectively).
12 supplier list of "F-AMidine"
-
25mg$1520.0050mg$1980.00100mg$2500.00
- Product Name:F-amidine
- Products Intro:Brand:TargetMol | Product Number:T24054
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:F-Amidine
- Products Intro:Brand：medicalisotopes | Product Number：46189
- Company Type: Reagent
- Country/Region: UNITED STATES
-
2.5mg$205.0025mg$1595.00
- Product Name:F-Amidine
- Products Intro:Brand:trc-canada | Product Number:F101250
- Company Type: Trader
- Country/Region: CANADA
- Product Name:F-AMidine
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:F-AMidine
- Products Intro:Package: 175USD/2.5mg;1400USD/25mg
- Company Type: Trader
- Country/Region: CANADA
- Product Name:F-Amidine
- Company Type: Trader
- Country/Region: CHINA
- Product Name:F-Amidine
- Company Type: Trader
- Country/Region: CHINA
- Product Name:F-Amidine
- Company Type: Trader
- Country/Region: CHINA
- Product Name:F-Amidine
- Products Intro:Brand:clearsynth | Product Number:CS-T-23411
- Company Type: Trader
- Country/Region: INDIA
- Product Name:F-Amidine
- Company Type: Trader
- Country/Region: CHINA
You can find F-AMidine suppliers,
manufacturers, and distributors from countries such as China, United States and the Canada here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.