Lamivudine manufacturers and suppliers

Lamivudine suppliers

Properties

Melting point:: 177 °C

Boiling point:: 475.4±55.0 °C(Predicted)

alpha: D21 -135° (c = 0.38 in methanol)

Density: 1.73±0.1 g/cm3(Predicted)

refractive index: -142 ° (C=1, MeOH)

Flash point:: 9℃

storage temp.: 2-8°C

solubility: water: soluble10mg/mL, clear

pka: 13.83±0.10(Predicted)

form: powder

color: white to beige

Water Solubility: 70g/L(temperature not stated)

Merck: 14,5352

BCS Class: 1,3

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

InChIKey: JTEGQNOMFQHVDC-NKWVEPMBSA-N

Safety Information

Symbol(GHS): GHS08

Signal word: Warning

Hazard statements: H361

Precautionary statements: P280

Risk Statements: 63-36/37/38

Safety Statements: 26-36

RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany: 3

RTECS: UW7361333

HS Code: 29349990

Use

Lamivudine is the (–) enantiomer of a cytidine analogue with sulfur substituted for the 3'carbon atom in the furanose ring [(–) 2',3'-dideoxy, 3'-thiacytidine]. It has significant activity in vitro against both HIV-1 and HIV-2 as well as HBV. Lamivudine is phosphorylated to the triphosphate metabolite by cellular kinases. The triphosphate derivative is a competitive inhibitor of the viral reverse transcriptase.

You can find Lamivudine suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.