methicillin manufacturers and suppliers

methicillin suppliers

methicillin

CAS:: 61-32-5

MF:: C17H20N2O6S

MW:: 380.42

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Properties

Boiling point:: 640.0±55.0 °C(Predicted)

Density: 1.44±0.1 g/cm3(Predicted)

pka: pKa 2.77± 0.04(H2O,t = 25,c=0.0097) (Uncertain)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P330-P501

Hazard Codes: Xn

Risk Statements: 22

WGK Germany: 3

RTECS: XH2379000

Use

2,6-Dimethoxyphenylpenicillin; methicillin (international non-proprietary name). The first β-lactamase-resistant semisynthetic penicillin. It was initially used widely but has been superseded by other group 3 members and is no longer commercially available. It is less active than benzylpenicillin or other group 3 penicillins. It is very stable to staphylococcal β-lactamase and is active against β-lactamaseproducing strains of Staph. aureus that do not produce a functional PBP 2a. Resistance is common among staphylococci, with the incidence geographically diverse. Most methicillin-resistant staphylococcal isolates display multiresistance. It is not acid resistant, and must therefore be administered parenterally. About 10% is metabolized, with 60–80% of the dose excreted in the urine. Toxicity is similar to that of other group 3 penicillins. Nephritis appears to be more common than with other penicillins.

You can find methicillin suppliers, manufacturers, and distributors from countries such as China, United States and the Switzerland here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.