Niraparib suppliers
Niraparib
- CAS:
- 1038915-60-4
- MF:
- C19H20N4O
- MW:
- 320.39
Suppliers by country/region
Company Type
Properties
- Melting point:
- 187-189°C
- Boiling point:
- 463.6±45.0 °C(Predicted)
- Density
- 1.34
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 15.36±0.30(Predicted)
- form
- Solid
- color
- Pale Yellow to Light Yellow
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H332-H335
- Precautionary statements
- P261-P280-P305+P351+P338
Use
The synthesis and initial pharmacology of niraparib have been published. Niraparib has affinity for PARP 1 and 2 inhibition (IC50 = 3.8 and 2.1 nM, respectively) and inhibits the proliferation of cancer cells with mutant BRCA1 and BRCA2 with IC50 values in the 10100 nM range in vitro. Niraparib demonstrated efficacy as a single agent in a xenograft model of BRCA1-deficient cancer. Niraparib has also been reported to act as a preclinical radiosensitiser and has entered into clinical oncology trials.
211 supplier list of "Niraparib"
- Product Name:Niraparib
- Products Intro:Purity: 99% | Package: 1kg; 25kg; 100kg or More
- Company Type: Manufacturer
- Country/Region: CHINA
- Product Name:Niraparib
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Dehydroepiandrosterone,Vardenafil,Tadalafil,Sildenafil citrate,Dapoxetine
$0.00-0.00 / 1kg
- Product Name:Niraparib
- Products Intro:Purity: 99.0% | Package: 1kg;|25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2-Chloromalonaldehyde,(R)-5,7-difluorochroman-4-ol,Cyclobutanecarboxylic acid,(Bromomethyl)cyclobutane,5-Amino-4-imidazolecarboxamide
$8.00-0.80 / 1kg
- Product Name: Niraparib
- Products Intro:Purity: 99% | Package: 1kg;8USD|25kg;2USD|100kg;0.8USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
- Product Name:Niraparib
- Products Intro:Purity: NLT 98% | Package: 1G;1KG;100KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
- Product Name:MK-4827 98.00%
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Niraparib
- Products Intro:Purity: As coa | Package: As request | CustNote: 1038915-60-4
- Company Type: Trader
- Country/Region: CHINA
- Product Name:MK-4827
- Products Intro:Purity: 0.99 | Package: 5MG;10MG;50MG;100MG,1G,5G
- Company Type: Reagent
- Country/Region: CHINA
