OCHRATOXIN A suppliers
OCHRATOXIN A
- CAS:
- 303-47-9
- MF:
- C20H18ClNO6
- MW:
- 403.81
Properties
- Melting point:
- 169°C
- alpha
- D -118° (c = 1.1 in CHCl3)
- Boiling point:
- 632.4±55.0 °C(Predicted)
- Density
- 1.2459 (rough estimate)
- refractive index
- 1.6000 (estimate)
- Flash point:
- 2 °C
- storage temp.
- 2-8°C
- solubility
- ethanol: soluble
- pka
- 3.29±0.10(Predicted)
- form
- powder
- color
- White to off-white
- Merck
- 13,6772
- BRN
- 8169012
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H300+H310+H330-H350-H360
- Precautionary statements
- P202-P260-P264-P280-P302+P352+P310-P304+P340+P310
- Hazard Codes
- T+,T,Xn,F
- Safety Statements
- 53-22-36/37/39-45-36-26-16-36/37-28-62
- RIDADR
- UN 3462 6.1/PG 2
- WGK Germany
- 3
- RTECS
- AY4375000
- F
- 10
- HazardClass
- 6.1(a)
- PackingGroup
- I
- HS Code
- 29322985
- Toxicity
- LD50 orally in rats: 20-22 mg/kg (Purchase, Theron)
Use
Ochratoxin A is a chlorinated benzopyran coupled to phenylalanine, produced by several Aspergillus and Penicillium sp. associated with food spoilage. Ochratoxins are widely distributed in the environment and are known to be nephrotoxic, teratogenic and possibly carcinogenic. Ochratoxin A may act by inducing DNA strand breaks, sister chromatid exchanges, DNA adduct formation, or reactive oxygen but the mechanism of action as a toxin is not yet resolved. At the molecular level, ochratoxin A specifically inhibits NK cell activity, increases growth of transplantable tumor cells in mice, increases apoptosis, activates c-Jun N terminal kinase in human kidney epithelial cells, and blocks metaphase/anaphase transition. It also inhibits plasminogen activator inhibitor-2 production by human blood mononuclear cells.
According to relevant laws, regulations, policies and the provisions of this website, this website does not display the product information!
The source is "剧毒、有毒、易致癌化学品". If the information is inaccurate, please contact the platform to modify it.
contact information：info@chemicalbook.com 400-158-660