ZARAGOZIC ACID A manufacturers and suppliers

Zaragozic acid A suppliers

ZARAGOZIC ACID A

CAS:: 142561-96-4

MF:: C35H46O14

MW:: 690.73

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Properties

alpha: D22 +18.3° (c = 0.60 in CHCl3); D25 +37° (c = 1.29 in methanol)

Boiling point:: 850.1±65.0 °C(Predicted)

Density: 1.35±0.1 g/cm3(Predicted)

storage temp.: −20°C

solubility: Soluble in DMSO

form: solid

pka: 1.47±0.70(Predicted)

color: white to light tan

Safety Information

WGK Germany: 3

Use

Zaragozic acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. In nature, zaragozic acid A acts as a broad spectrum antifungal but its mode of action as an inhibitor of squalene synthase, involved in sterol biosynthesis, led to investigation as a cholesterol lowering agent. Zaragozic acid A prepared by BioAustralis is presented as the free acid rather than the tri-sodium salt to avoid stability problems associated with hydrolysis of the salt.

You can find Zaragozic acid A suppliers, manufacturers, and distributors from countries such as China, United States and the Switzerland here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.