zerumbone manufacturers and suppliers

zerumbone suppliers

zerumbone

CAS:: 471-05-6

MF:: C15H22O

MW:: 218.33

Suppliers by country/region

Company Type

Properties

Melting point:: 67-69℃

Boiling point:: 321.6±42.0 °C(Predicted)

Density: 0.887±0.06 g/cm3(Predicted)

storage temp.: 2-8°C

solubility: DMSO: ≥10mg/mL

form: powder

color: white to off-white

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

LogP: 4.168 (est)

Safety Information

Symbol(GHS): GHS07,GHS09

Signal word: Warning

Hazard statements: H317-H400

Precautionary statements: P273-P280-P302+P352

Hazard Codes: Xi,N

Risk Statements: 43-50

Safety Statements: 36/37-60-61

RIDADR: UN 3077 9 / PGIII

WGK Germany: 3

Use

Zerumbone is isolated from the rhizomes of the wild ginger Zingiber zerumbet. It isfound to suppress the proliferation of breast cancer and colon cancer cells and alsoto prevent initiation and promotion of skin cancer in mice. It also suppresses theNF-κB activation and its sequential suppression of IκBα kinase activity, IκBαphosphorylation, IκBα degradation, p65 phosphorylation, nuclear translocation,and acylation. It downregulates the NF-κB-regulated gene products like FLIP, cyclinD1, TRAF1, COX2, Bfl-1/A1, MMP-9, Bcl-xL, ICAM-1, Bcl-2, c-myc, XIAP,survivin, IAP1, and IAP2, and thus, it potentiates apoptosis (Murakami et al. 2002;Sakinah et al. 2007).

You can find zerumbone suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.