1,9-Pyrazoloanthrone
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- $5 - $1390
- Product name: 1,9-Pyrazoloanthrone
- CAS: 129-56-6
- MF: C14H8N2O
- MW: 220.23
- EINECS:204-955-6
- MDL Number:MFCD00022289
- Synonyms:Dibenzo[cd,g]indazol-6(2H)-one;Nsc75890;Wln: T C6665 1A p iv omnj;SP600125 >99%;JNK Inhibitor II, 1,9-Pyrazoloanthrone;c.i.70300 ;SAPK INHIBITOR I;SAPK INHIBITOR II
101 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 5mg
- 10mg
- 20mg
- 25mg
- 50
- 1mg
- 10
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 2.5G
- 5g
- 10g
- 25g
- 100g
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone ≥98%
- Packaging25mg
- Price$14
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging50mg
- Price$19
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging100mg
- Price$23
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging250mg
- Price$28
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging1g
- Price$29
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging5g
- Price$63
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging10g
- Price$107
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging25g
- Price$196
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000YOL
- Product description1,9-Pyrazoloanthrone 98%
- Packaging100g
- Price$607
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10386
- Product descriptionSP600125 98%
- Packaging25G
- Price$885
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10386
- Product descriptionSP600125 98%
- Packaging5G
- Price$240
- Updated2026-05-25
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3549-M005
- Product descriptionSP600125 ≥98%
- Packaging5mg
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3549-M001
- Product descriptionSP600125 ≥98%
- Packaging1mg
- Price$20
- Updated2026-05-06
- Buy
- ManufacturerAHH
- Product numberMT-21875
- Product description1,9-Pyrazoloanthrone 98%
- Packaging5g
- Price$388
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-21875
- Product description1,9-Pyrazoloanthrone 97%
- Packaging5g
- Price$388
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-21875
- Product description1,9-Pyrazoloanthrone 97%
- Packaging5g
- Price$388
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone ≥98% | 25mg | $14 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 50mg | $19 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 100mg | $23 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 250mg | $28 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 1g | $29 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 5g | $63 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 10g | $107 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 25g | $196 | 2026-05-25 | Buy |
| aablocks | AA000YOL | 1,9-Pyrazoloanthrone 98% | 100g | $607 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10386 | SP600125 98% | 25G | $885 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10386 | SP600125 98% | 5G | $240 | 2026-05-25 | Buy |
| Adipogen Life Sciences | AG-CR1-3549-M005 | SP600125 ≥98% | 5mg | $60 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3549-M001 | SP600125 ≥98% | 1mg | $20 | 2026-05-06 | Buy |
| AHH | MT-21875 | 1,9-Pyrazoloanthrone 98% | 5g | $388 | 2021-12-16 | Buy |
| AHH | MT-21875 | 1,9-Pyrazoloanthrone 97% | 5g | $388 | 2026-05-25 | Buy |
| AHH | MT-21875 | 1,9-Pyrazoloanthrone 97% | 5g | $388 | 2026-05-26 | Buy |
Properties
Melting point :281~282℃
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H2O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChI :InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
SMILES :N1=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)
Boiling point :361.16°C (rough estimate)
Density :1.1702 (rough estimate)
refractive index :1.5910 (estimate)
storage temp. :2-8°C
solubility :H2O: insoluble
form :Yellowish orange solid
pka :11.75±0.20(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChI :InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)
InChIKey :ACPOUJIDANTYHO-UHFFFAOYSA-N
SMILES :N1=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1
CAS DataBase Reference :129-56-6(CAS DataBase Reference)
EPA Substance Registry System :Anthra[1,9-cd]pyrazol-6(2H)-one (129-56-6)
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
SP 600125 is a potent and reversible inhibitor of JNK1-3 with an IC50 value of 0.11 ?M.1 It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells, blocking the expression of COX-2 and TNF-α in monocytes and IL-10, TNF-α, and IFN-γ in T-cells. SP 600125 also prevents apoptosis in many cell types, including B-cells, and inhibits autophagy in HeLa cells. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes (IC50 > 10 ?M). Active in vivo. Shown to have reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis. Prevents BMP9-induced osteogenic differentiation of MSCs.Related product price
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