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ChemicalBook >> CAS DataBase List >> Furosemide

Furosemide

Furosemide price.
  • $22 - $2148.3
  • Product name: Furosemide
  • CAS: 54-31-9
  • MF: C12H11ClN2O5S
  • MW: 330.74
  • EINECS:200-203-6
  • MDL Number:MFCD00010549
  • Synonyms:5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID;5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID;LABOTEST-BB LT00244801;FUROSEMIDE;2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid;FUROSEMIDE METHANOL SOLUTION;FUROSEMIDE, RELATED COMPOUND B 4-CHLORO-5-SULFAMOYLANTHRANILIC ACID USP STANDARD;FUROSEMIDE, EP STANDARD
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  • Abosyn
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Aronis compounds
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
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  • Tocris
  • TRC
Package
  • y0001493
  • 10μg
  • 1mg
  • 5mg
  • 50mg
  • 100mg
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  • 1mL
  • 5ml
  • 50
  • 1G
  • 5g
  • 10g
  • f0700000
  • 25g
  • 50g
  • 100g
  • 400μL
  • 10mM(in 1mL DMSO)
  • ManufacturerAbosyn
  • Product number30-1084
  • Product descriptionFurosemide 95%-98%
  • Packaging25g
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1543
  • Product descriptionFurosemide 98%
  • Packaging100g
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ40149
  • Product descriptionFurosemide
  • Packaging50mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61457
  • Product descriptionFurosemide, 97+%
  • Packaging5g
  • Price$98.7
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ61457
  • Product descriptionFurosemide, 97+%
  • Packaging10g
  • Price$164
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ61457
  • Product descriptionFurosemide, 97+%
  • Packaging25g
  • Price$310
  • Updated2024-03-01
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002772
  • Product descriptionFUROSEMIDE 95.00%
  • Packaging1G
  • Price$123.9
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002772
  • Product descriptionFUROSEMIDE 95.00%
  • Packaging10G
  • Price$2148.3
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8435
  • Product descriptionFurosemide
  • Packaging1g
  • Price$42
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8435
  • Product descriptionFurosemide
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8435
  • Product descriptionFurosemide
  • Packaging5g
  • Price$143
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR5475
  • Product description4-Chloro-2-{[(fur-2-yl)methyl]amino}-5-sulphamoylbenzoicacid
  • Packaging5g
  • Price$37
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR5475
  • Product description4-Chloro-2-{[(fur-2-yl)methyl]amino}-5-sulphamoylbenzoicacid
  • Packaging25g
  • Price$98
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR5475
  • Product description4-Chloro-2-{[(fur-2-yl)methyl]amino}-5-sulphamoylbenzoicacid
  • Packaging100g
  • Price$201
  • Updated2021-12-16
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  • ManufacturerAronis compounds
  • Product numberBBC/460
  • Product description5-(aminosulfonyl)-4-chloro-2-[(2-furylmethyl)amino]benzoicacid
  • Packaging1g
  • Price$22
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb528269
  • Product descriptionTMEM173
  • Packaging10μg
  • Price$290.7
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 30-1084 Furosemide 95%-98% 25g $480 2021-12-16 Buy
AHH API-1543 Furosemide 98% 100g $380 2021-12-16 Buy
AK Scientific J40149 Furosemide 50mg $68 2021-12-16 Buy
Alfa Aesar J61457 Furosemide, 97+% 5g $98.7 2024-03-01 Buy
Alfa Aesar J61457 Furosemide, 97+% 10g $164 2024-03-01 Buy
Alfa Aesar J61457 Furosemide, 97+% 25g $310 2024-03-01 Buy
American Custom Chemicals Corporation API0002772 FUROSEMIDE 95.00% 1G $123.9 2021-12-16 Buy
American Custom Chemicals Corporation API0002772 FUROSEMIDE 95.00% 10G $2148.3 2021-12-16 Buy
ApexBio Technology A8435 Furosemide 1g $42 2021-12-16 Buy
ApexBio Technology A8435 Furosemide 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A8435 Furosemide 5g $143 2021-12-16 Buy
Apolloscientific OR5475 4-Chloro-2-{[(fur-2-yl)methyl]amino}-5-sulphamoylbenzoicacid 5g $37 2021-12-16 Buy
Apolloscientific OR5475 4-Chloro-2-{[(fur-2-yl)methyl]amino}-5-sulphamoylbenzoicacid 25g $98 2021-12-16 Buy
Apolloscientific OR5475 4-Chloro-2-{[(fur-2-yl)methyl]amino}-5-sulphamoylbenzoicacid 100g $201 2021-12-16 Buy
Aronis compounds BBC/460 5-(aminosulfonyl)-4-chloro-2-[(2-furylmethyl)amino]benzoicacid 1g $22 2021-12-16 Buy
Biorbyt Ltd orb528269 TMEM173 10μg $290.7 2021-12-16 Buy

Properties

Melting point :220 °C (dec.) (lit.)
Boiling point :582.1±60.0 °C(Predicted)
Density :1.606
refractive index :1.6580 (estimate)
Flash point :11 °C
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
pka :pKa 3.8 (Uncertain)
form :powder
color :White to Off-White
Water Solubility :Soluble in acetone, DMF or methanol. Slightly soluble in water
Merck :14,4309
BCS Class :2 (CLogP), 4 (LogP)
Stability :Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.
InChIKey :ZZUFCTLCJUWOSV-UHFFFAOYSA-N
CAS DataBase Reference :54-31-9(CAS DataBase Reference)
IARC :3 (Vol. 50) 1990
EPA Substance Registry System :Furosemide (54-31-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Furosemide is an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Ki = ~10 μM for each). It is commonly used as a loop diuretic, blocking NKCC2 action on the apical membrane of the thick ascending limb of Henle epithelial cells. Furosemide also acts as an antagonist of GABAA receptors and as an inhibitor of carbonic anhydrase and organic anion transporter 1.

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