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ChemicalBook >> CAS DataBase List >> [4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone

[4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone

[4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone price.
  • $35 - $2583.16
  • Product name: [4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone
  • CAS: 1000669-72-6
  • MF: C20H20N4O
  • MW: 332.4
  • EINECS:
  • MDL Number:MFCD18385006
  • Synonyms:[4-[2-(1H-Indazol-3-yl)ethenyl]phenyl]-1-piperazinylmethanone;KW 2449;(E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone;KW2449(E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanonehydrochloride;KW-2449;KW 2449; KW2449;[4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone;KW-2449 100MG;{4-[(E)-2-(1H-Indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone
19 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 5mg
  • 25mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 10MG
  • 50mg
  • 100MG
  • ManufacturerAK Scientific
  • Product numberX7371
  • Product description(E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000938
  • Product descriptionKW-2449 95.00%
  • Packaging10MG
  • Price$656
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000938
  • Product descriptionKW-2449 95.00%
  • Packaging50MG
  • Price$1734.23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000938
  • Product descriptionKW-2449 95.00%
  • Packaging100MG
  • Price$2583.16
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4123
  • Product descriptionKW2449
  • Packaging10mM(in 1mL DMSO)
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22207
  • Product descriptionKW 2449 ≥98%
  • Packaging50mg
  • Price$263
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22207
  • Product descriptionKW 2449 ≥98%
  • Packaging25mg
  • Price$149
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22207
  • Product descriptionKW 2449 ≥98%
  • Packaging10mg
  • Price$67
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22207
  • Product descriptionKW 2449 ≥98%
  • Packaging5mg
  • Price$35
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM150821
  • Product description(E)-(4-(2-(1H-Indazol-3-yl)vinyl)-phenyl)(piperazin-1-yl)methanone 98%
  • Packaging100mg
  • Price$335
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0231
  • Product descriptionKW-2449 99.85%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0231
  • Product descriptionKW-2449 99.85%
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0231
  • Product descriptionKW-2449 99.85%
  • Packaging50mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0231
  • Product descriptionKW-2449 99.85%
  • Packaging100mg
  • Price$576
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004900
  • Product descriptionKW-2449 98+%
  • Packaging10mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004900
  • Product descriptionKW-2449 98+%
  • Packaging50mg
  • Price$195
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7371 (E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone 50mg $290 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000938 KW-2449 95.00% 10MG $656 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000938 KW-2449 95.00% 50MG $1734.23 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000938 KW-2449 95.00% 100MG $2583.16 2021-12-16 Buy
ApexBio Technology A4123 KW2449 10mM(in 1mL DMSO) $88 2021-12-16 Buy
Cayman Chemical 22207 KW 2449 ≥98% 50mg $263 2024-03-01 Buy
Cayman Chemical 22207 KW 2449 ≥98% 25mg $149 2024-03-01 Buy
Cayman Chemical 22207 KW 2449 ≥98% 10mg $67 2024-03-01 Buy
Cayman Chemical 22207 KW 2449 ≥98% 5mg $35 2024-03-01 Buy
Chemenu CM150821 (E)-(4-(2-(1H-Indazol-3-yl)vinyl)-phenyl)(piperazin-1-yl)methanone 98% 100mg $335 2021-12-16 Buy
ChemScene CS-0231 KW-2449 99.85% 5mg $60 2021-12-16 Buy
ChemScene CS-0231 KW-2449 99.85% 10mg $84 2021-12-16 Buy
ChemScene CS-0231 KW-2449 99.85% 50mg $312 2021-12-16 Buy
ChemScene CS-0231 KW-2449 99.85% 100mg $576 2021-12-16 Buy
Crysdot CD31004900 KW-2449 98+% 10mg $46 2021-12-16 Buy
Crysdot CD31004900 KW-2449 98+% 50mg $195 2021-12-16 Buy

Properties

Boiling point :604.1±55.0 °C(Predicted)
Density :1.28
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :13.76±0.40(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

KW-2449 is a potent multikinase inhibitor (IC50’s: FLT3 = 7 nM, FGFR1 = 36 nM, Abl = 14 nM, Abl-T315 = 4 nM) with anti-leukemic effects.1,2,3