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ChemicalBook >> CAS DataBase List >> 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-

1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-

1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)- price.
  • $20 - $1200
  • Product name: 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-iMidazole-5,2-diyl)bis-, 1,1'-bis(1,1-diMethylethyl) ester, (2S,2'S)-
  • CAS: 1007882-23-6
  • MF: C36H44N6O4
  • MW: 624.77236
  • EINECS:1592732-453-0
  • MDL Number:MFCD28404669
  • Synonyms:(2S,2'S)-2,2'-[(1,1'-biphenyl)-4,4'-diyldi-1H-imidazole-5,2-diyl]bis-1-pyrrolidinecarboxylic acid ,1,1'-bis(1,1-dimethylethyl) ester;Daclatasvir Intermediates Ⅱ;Dacaltasvir Intermediate 02;Daclatasvir Intermediates;di-tert-butyl2,2'-([1,1'-biphenyl]-4,4'-diylbis(1H-imidazole-5,2-diyl))(2S,2'S)-bis(pyrrolidine-1-carboxylate);Methyl-N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate;Daclatasvir Intermediates 4;Bis(2-methyl-2-propanyl) (2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate)
Price37 Properties Safety Information Description
37 prices
Selected condition：
Brand
  • aablocks
  • Alichem
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Chemenu
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • 25g
  • Manufactureraablocks
  • Product numberAA0002SS
  • Product description1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98%
  • Packaging25mg
  • Price$124
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA0002SS
  • Product description1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98%
  • Packaging100mg
  • Price$258
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA0002SS
  • Product description1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98%
  • Packaging50mg
  • Price$180
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA0002SS
  • Product description1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98%
  • Packaging500mg
  • Price$535
  • Updated2026-05-25
  • Buy
  • ManufacturerAlichem
  • Product number1007882236
  • Product descriptionBIs(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate)
  • Packaging10g
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1007882236
  • Product descriptionBIs(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate)
  • Packaging25g
  • Price$1009.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203689
  • Product descriptionBis(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+%
  • Packaging5g
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203689
  • Product descriptionBis(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+%
  • Packaging10g
  • Price$52
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203689
  • Product descriptionBis(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+%
  • Packaging25g
  • Price$52
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5618
  • Product descriptionmethyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA1879
  • Product descriptionHCV-IN-30
  • Packaging25mg
  • Price$72
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA1879
  • Product descriptionHCV-IN-30
  • Packaging100mg
  • Price$180
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5618
  • Product descriptionmethyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
  • Packaging10mM(in 1mL DMSO)
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA1879
  • Product descriptionHCV-IN-30
  • Packaging50mg
  • Price$117
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5618
  • Product descriptionmethyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
  • Packaging25mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5618
  • Product descriptionmethyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
  • Packaging100mg
  • Price$610
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0002SS 1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98% 25mg $124 2026-05-25 Buy
aablocks AA0002SS 1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98% 100mg $258 2026-05-25 Buy
aablocks AA0002SS 1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98% 50mg $180 2026-05-25 Buy
aablocks AA0002SS 1,1'-Bis(1,1-dimethylethyl) (2S,2'S)-2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis[1-pyrrolidinecarboxylate] >98% 500mg $535 2026-05-25 Buy
Alichem 1007882236 BIs(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 10g $510 2021-12-16 Buy
Alichem 1007882236 BIs(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 25g $1009.4 2021-12-16 Buy
Ambeed A203689 Bis(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+% 5g $29 2021-12-16 Buy
Ambeed A203689 Bis(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+% 10g $52 2021-12-16 Buy
Ambeed A203689 Bis(2-methyl-2-propanyl)(2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate) 95+% 25g $52 2021-12-16 Buy
ApexBio Technology A5618 methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate 5mg $65 2021-12-16 Buy
ApexBio Technology BA1879 HCV-IN-30 25mg $72 2026-05-06 Buy
ApexBio Technology BA1879 HCV-IN-30 100mg $180 2026-05-06 Buy
ApexBio Technology A5618 methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate 10mM(in 1mL DMSO) $100 2021-12-16 Buy
ApexBio Technology BA1879 HCV-IN-30 50mg $117 2026-05-06 Buy
ApexBio Technology A5618 methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate 25mg $220 2021-12-16 Buy
ApexBio Technology A5618 methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate 100mg $610 2021-12-16 Buy
Next Last

Properties

Boiling point :890.2±65.0 °C(Predicted)
Density :1.220±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :12.83±0.10(Predicted)
color :White to Off-White
InChIKey :WPMTYMFNINZZHE-WBOANQFRNA-N
SMILES :C1(C2=CC=C(C3NC([C@@H]4CCCN4C(OC(C)(C)C)=O)=NC=3)C=C2)=CC=C(C2NC([C@@H]3CCCN3C(OC(C)(C)C)=O)=NC=2)C=C1 |&1:8,30,r|

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Flame Over Circle (GHS03)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H272 May intensify fire; oxidizer Oxidising liquids;Oxidising solids Category 2
Category 3		 Danger
Warning		 P210, P220, P221P280, P370+P378,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P220 Keep/Store away from clothing/…/combustible materials.
P221 Take any precaution to avoid mixing with combustibles/…
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P501 Dispose of contents/container to..…

Description

(2S,2''S)-2,2''-([1,1''-Biphenyl]-4,4''-diyldi-1H-imidazole-5,2-diyl)bis-1-pyrrolidinecarboxylic Acid 1,1''-Bis(1,1-dimethylethyl) Ester is an antiviral agent and Daclatasvir (D101500) intermediate. Daclatasvir inhibits the HCV protein NS5A and thus can be used as a drug candidate for the treatment of hepatitis C (HCV).

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4,4'-Bis(2-bromoacetyl)biphenyl dimethyl (2S,2'S)-1,1'-((2S,2'S)-2,2'-(4,4'-(biphenyl-4,4'-diyl)bis(1H-imidazole-4,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methyl-1-oxobutane-2,1-diyl)dicarbamate

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Suppliers and manufacturers

ChemFuture PharmaTech (Jiangsu) Ltd Energy Chemical Nanjing Chemlin Chemical Co., Ltd Shanghai Hanhong Scientific Co.,Ltd. XiaoGan ShenYuan ChemPharm co,ltd BOC Sciences Changzhou Joyous Chemical Co., Ltd. Shanghai T&W Pharmaceutical Co., Ltd. Hunan Furui Biopharma Technology Co., Ltd. Shanghai Twisun Bio-pharm Co.,Ltd