3-PYRIDINECARBOXAMIDE, 6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]-
- $121 - $3811.5
- Product name: 3-PYRIDINECARBOXAMIDE, 6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]-
- CAS: 1033836-12-2
- MF: C19H19F4N3O
- MW: 381.37
- EINECS:
- MDL Number:MFCD18206776
- Synonyms:HPGDS inhibitor 1;6-(3-Fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]-3-pyridinecarboxamide;3-PYRIDINECARBOXAMIDE, 6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]-;6-(3-fluorophenyl)-N-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)nicotinaMide;HPGDS inhibitor 1, >=98%;Prostaglandin D Synthase (hematopoietic-type) Inhibitor I;CS-1438;MDK36122
14 prices
Selected condition:
Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 100mg
- 250mg
- 1g
- 1000mg
- 5G
- ManufacturerAmbeed
- Product numberA414719
- Product descriptionHPGDSinhibitor1 98+%
- Packaging100mg
- Price$1282
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0316558
- Product description6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]-3-PYRIDINECARBOXAMIDE 95.00%
- Packaging5G
- Price$3811.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1046
- Product descriptionHPGDSinhibitor1
- Packaging100mg
- Price$2051
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181253
- Product descriptionHPGDS-inhibitor-1 >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181253
- Product descriptionHPGDS-inhibitor-1 >98%
- Packaging250mg
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181253
- Product descriptionHPGDS-inhibitor-1 >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16256
- Product descriptionProstaglandin D Synthase (hematopoietic-type) Inhibitor I ≥98%
- Packaging1mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16256
- Product descriptionProstaglandin D Synthase (hematopoietic-type) Inhibitor I ≥98%
- Packaging5mg
- Price$302
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16256
- Product descriptionProstaglandin D Synthase (hematopoietic-type) Inhibitor I ≥98%
- Packaging10mg
- Price$543
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1801
- Product descriptionHPGDSinhibitor1 99.32%
- Packaging100mg
- Price$1680
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004772
- Product descriptionHPGDSinhibitor1 98+%
- Packaging100mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004772
- Product descriptionHPGDSinhibitor1 98+%
- Packaging250mg
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7424
- Product descriptionHPGDS-inhibitor-1 >98%
- Packaging250mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7424
- Product descriptionHPGDS-inhibitor-1 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Ambeed | A414719 | HPGDSinhibitor1 98+% | 100mg | $1282 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0316558 | 6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]-3-PYRIDINECARBOXAMIDE 95.00% | 5G | $3811.5 | 2021-12-16 | Buy |
ApexBio Technology | B1046 | HPGDSinhibitor1 | 100mg | $2051 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181253 | HPGDS-inhibitor-1 >98% | 100mg | $765 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181253 | HPGDS-inhibitor-1 >98% | 250mg | $1504.5 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181253 | HPGDS-inhibitor-1 >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
Cayman Chemical | 16256 | Prostaglandin D Synthase (hematopoietic-type) Inhibitor I ≥98% | 1mg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 16256 | Prostaglandin D Synthase (hematopoietic-type) Inhibitor I ≥98% | 5mg | $302 | 2024-03-01 | Buy |
Cayman Chemical | 16256 | Prostaglandin D Synthase (hematopoietic-type) Inhibitor I ≥98% | 10mg | $543 | 2024-03-01 | Buy |
ChemScene | CS-1801 | HPGDSinhibitor1 99.32% | 100mg | $1680 | 2021-12-16 | Buy |
Crysdot | CD31004772 | HPGDSinhibitor1 98+% | 100mg | $250 | 2021-12-16 | Buy |
Crysdot | CD31004772 | HPGDSinhibitor1 98+% | 250mg | $430 | 2021-12-16 | Buy |
DC Chemicals | DC7424 | HPGDS-inhibitor-1 >98% | 250mg | $1000 | 2021-12-16 | Buy |
DC Chemicals | DC7424 | HPGDS-inhibitor-1 >98% | 1g | $1800 | 2021-12-16 | Buy |
Properties
Boiling point :487.2±45.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.55±0.20(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.55±0.20(Predicted)
Safety Information
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Description
Prostaglandin D2 is synthesized by PGD synthase (hematopoietic-type) (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Thus, H-PGDS is an important target for the development of inhibitors for therapeutic use against these diseases. H-PGDS inhibitor I selectively blocks HPGDS (IC50s = 0.7 and 32 nM in enzyme and cellular assays, respectively) with little activity against the related human enzymes L-PGDS, mPGES, COX-1, COX-2, and 5-LOX. It is orally bioavailable and has been shown to dampen airway hyper-responsiveness in a model of antigen-induced airway response in allergic sheep.Related product price
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$9.80 /1.79999995231628KG
3-PYRIDINECARBOXAMIDE, 6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]- CAS:1033836-12-2
3-PYRIDINECARBOXAMIDE, 6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]- CAS:1033836-12-2