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ChemicalBook >> CAS DataBase List >> 5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one

5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one

5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one price.
  • $27 - $2691.1
  • Product name: 5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one
  • CAS: 1048371-03-4
  • MF: C17H13NO3
  • MW: 279.29
  • EINECS:
  • MDL Number:MFCD14051631
  • Synonyms:5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one;UPF 1069;5-(2-Oxo-2-phenylethoxy)-1(2H)-isoquinolinone;1(2H)-Isoquinolinone, 5-(2-oxo-2-phenylethoxy)-;UPF 1069;UPF-1069; UPF1069;UPF 1069 10MG;UPF1069/UPF-1069;CS-874
32 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • ManufacturerAK Scientific
  • Product number2785AH
  • Product description5-Phenacyloxy-2H-isoquinolin-1-one
  • Packaging2mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2785AH
  • Product description5-Phenacyloxy-2H-isoquinolin-1-one
  • Packaging5mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA906956
  • Product descriptionUPF-1069 98+%
  • Packaging1mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA906956
  • Product descriptionUPF-1069 98+%
  • Packaging5mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA906956
  • Product descriptionUPF-1069 98+%
  • Packaging10mg
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA906956
  • Product descriptionUPF-1069 98+%
  • Packaging50mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA906956
  • Product descriptionUPF-1069 98+%
  • Packaging100mg
  • Price$306
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001212
  • Product descriptionUPF 1069 95.00%
  • Packaging5MG
  • Price$500.17
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4163
  • Product descriptionUPF1069
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4163
  • Product descriptionUPF1069
  • Packaging10mM(in 1mL DMSO)
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4163
  • Product descriptionUPF1069
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2369
  • Product descriptionUPF1069 99%
  • Packaging50mg
  • Price$247.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180867
  • Product descriptionUPF 1069 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180867
  • Product descriptionUPF 1069 >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180867
  • Product descriptionUPF 1069 >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17760
  • Product descriptionUPF-1069 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2785AH 5-Phenacyloxy-2H-isoquinolin-1-one 2mg $113 2021-12-16 Buy
AK Scientific 2785AH 5-Phenacyloxy-2H-isoquinolin-1-one 5mg $142 2021-12-16 Buy
Ambeed A906956 UPF-1069 98+% 1mg $27 2021-12-16 Buy
Ambeed A906956 UPF-1069 98+% 5mg $53 2021-12-16 Buy
Ambeed A906956 UPF-1069 98+% 10mg $91 2021-12-16 Buy
Ambeed A906956 UPF-1069 98+% 50mg $235 2021-12-16 Buy
Ambeed A906956 UPF-1069 98+% 100mg $306 2021-12-16 Buy
American Custom Chemicals Corporation INB0001212 UPF 1069 95.00% 5MG $500.17 2021-12-16 Buy
ApexBio Technology A4163 UPF1069 10mg $90 2021-12-16 Buy
ApexBio Technology A4163 UPF1069 10mM(in 1mL DMSO) $99 2021-12-16 Buy
ApexBio Technology A4163 UPF1069 50mg $290 2021-12-16 Buy
Axon Medchem Axon2369 UPF1069 99% 50mg $247.5 2021-12-16 Buy
Biorbyt Ltd orb180867 UPF 1069 >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb180867 UPF 1069 >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb180867 UPF 1069 >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 17760 UPF-1069 ≥98% 1mg $32 2024-03-01 Buy

Properties

storage temp. :Store at RT
solubility :Soluble in DMSO (up to 40 mg/ml).
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. UPF-1069 is a PARP inhibitor that demonstrates a modest preference for PARP2 over PARP1 (IC50s = 0.3 and 8 μM, respectively). In rat models of post-ischemic brain damage, it has been shown to increase cell death in hippocampal slice cultures in a model characterized by loss of neurons through a caspase-dependent, apoptosis-like process but to be protective of cortical neurons in a model characterized by a necrosis-like process.

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