Olaparib
|
- $28 - $2147.1
- Product name: Olaparib
- CAS: 763113-22-0
- MF: C24H23FN4O3
- MW: 434.46
- EINECS:642-941-5
- MDL Number:MFCD13185161
- Synonyms:1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin;Olaparid AZD2281;4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]Methyl]-1(2H)-phthalazinone;KU 59436;AZD2281(olaparib)/AZD-2281;AZD2281(olaparib);4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one;Olaparib-D8
63 prices
Selected condition：
Brand
- AccelPharmtech
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1unit
- 5mg
- 10MG
- 20mg
- 25mg
- 50MG
- 2x25mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1G
- 2g
- 5G
- 10G
- 25G
- 10mM(in 1mL DMSO)
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging1G
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging5G
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging10G
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberCF1283
- Product descriptionOlaparib 99%
- Packaging25G
- Price$1910
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-3043-M100
- Product descriptionOlaparib ≥95%
- Packaging100mg
- Price$594
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ93043
- Product descriptionOlaparib
- Packaging250mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ93043
- Product descriptionOlaparib
- Packaging1g
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberB673
- Product descriptionOlaparib
- Packaging1g
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024518
- Product descriptionOLAPARIB 95.00%
- Packaging10MG
- Price$154.35
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024518
- Product descriptionOLAPARIB 95.00%
- Packaging50MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging100mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4154
- Product descriptionOlaparib(AZD2281,Ku-0059436)
- Packaging500mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60045
- Product descriptionOlaparib(AZD2281) ≥98%
- Packaging20mg
- Price$148
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AccelPharmtech | CF1283 | Olaparib 99% | 1G | $130 | 2021-12-16 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 5G | $230 | 2021-12-16 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 10G | $1050 | 2021-12-16 | Buy |
| AccelPharmtech | CF1283 | Olaparib 99% | 25G | $1910 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-3043-M100 | Olaparib ≥95% | 100mg | $594 | 2021-12-16 | Buy |
| AK Scientific | J93043 | Olaparib | 250mg | $49 | 2021-12-16 | Buy |
| AK Scientific | J93043 | Olaparib | 1g | $110 | 2021-12-16 | Buy |
| AK Scientific | B673 | Olaparib | 1g | $300 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024518 | OLAPARIB 95.00% | 10MG | $154.35 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024518 | OLAPARIB 95.00% | 50MG | $721.88 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 10mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 100mg | $160 | 2021-12-16 | Buy |
| ApexBio Technology | A4154 | Olaparib(AZD2281,Ku-0059436) | 500mg | $480 | 2021-12-16 | Buy |
| Arctom | CFN60045 | Olaparib(AZD2281) ≥98% | 20mg | $148 | 2021-12-16 | Buy |
Properties
Density :1.43
storage temp. :-20°C
solubility :Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
pka :12.07±0.40(Predicted)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)=NN1
CAS DataBase Reference :763113-22-0
storage temp. :-20°C
solubility :Soluble in DMSO (up to 33 mg/ml) or in Ethanol (up to 1.7 mg/ml)
pka :12.07±0.40(Predicted)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :FDLYAMZZIXQODN-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C=CC=C2)C(CC2=CC=C(F)C(C(N3CCN(C(C4CC4)=O)CC3)=O)=C2)=NN1
CAS DataBase Reference :763113-22-0
Safety Information
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| Signal word: | Danger | ||||||||||||||||
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Description
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.More related product prices
2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide BMN 673 871700-17-3 PF-01367338 Bortezomib 1021298-67-8 59878-57-8 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid Nintedanib Ethanesulfonate Salt PLERIXAFOR Afatinib (BIBW 2992) Crizotinib 4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one 3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid 918504-65-1Related product price
- 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-
carboxamide
$28-4644 - BMN 673
$28-2839 - 871700-17-3
$28-4391.1
Suppliers and manufacturers
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
Zhengzhou Anhuida Chemical Co., Ltd
Jewim Pharmaceutical (Shandong) Co., Ltd.
Seasons Biotechnology Co., Ltd.
Hefei TianRui Pharmaceutical Chemical Co., Ltd.
SHANDONG BOYUAN PHARMACEUTICAL CO., LTD.
