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ChemicalBook >> CAS DataBase List >> 4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-1,1-dioxide

4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-1,1-dioxide

$100 - $1800
Product name: 4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-1,1-dioxide
CAS: 108477-18-5
MF: C19H14N2O7S
MW: 414.39
EINECS:
MDL Number:MFCD28138111
Synonyms:4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-1,1-dioxide;NSC-144303;Ubiquitin Isopeptidase Inhibitor I;Ubiquitin Isopeptidase Inhibitor I, G5;G5, Ubiquitin Isopeptidase Inhibitor I;Ubiquitin Isopeptidase-IN-G5;Ubiquitin Isopeptidase Inhibitor I, G5 (NSC144303);Ubiquitin Isopeptidase Inhibitor I, G5,Ubiquitin Isopeptidase Inhibitor I, G-5

Price19 Properties Safety Information Description

19 prices

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Brand

ACHEMBLOCK
AK Scientific
ApexBio Technology
Biosynth
Cayman Chemical
CSNpharm
DC Chemicals
Sigma-Aldrich
TRC

Package

5mg
10mg
25MG
50mg
100MG
250MG
1g

ManufacturerACHEMBLOCK
Product numberAD268620
Product descriptionUbiquitin Isopeptidase Inhibitor I, G5 98%
Packaging25MG
Price$110
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberAD268620
Product descriptionUbiquitin Isopeptidase Inhibitor I, G5 98%
Packaging100MG
Price$190
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberAD268620
Product descriptionUbiquitin Isopeptidase Inhibitor I, G5 98%
Packaging250MG
Price$340
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number5032CP
Product descriptionUbiquitinIsopeptidaseInhibitorI,G5
Packaging5mg
Price$206
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberC3250
Product descriptionUbiquitin Isopeptidase Inhibitor I
Packaging25mg
Price$347
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberC3250
Product descriptionUbiquitin Isopeptidase Inhibitor I
Packaging10mg
Price$174
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberC3250
Product descriptionUbiquitin Isopeptidase Inhibitor I
Packaging5mg
Price$100
Updated2026-05-06
Buy

ManufacturerBiosynth
Product numberIEA47718
Product descriptionUbiquitin Isopeptidase Inhibitor I, G5
Packaging50mg
Price$1117.5
Updated2026-06-04
Buy

ManufacturerBiosynth
Product numberIEA47718
Product descriptionUbiquitin Isopeptidase Inhibitor I, G5
Packaging100mg
Price$1555
Updated2026-06-04
Buy

ManufacturerCayman Chemical
Product number21006
Product descriptionUbiquitin Isopeptidase Inhibitor I ≥98%
Packaging25mg
Price$396
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number21006
Product descriptionUbiquitin Isopeptidase Inhibitor I ≥98%
Packaging10mg
Price$193
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number21006
Product descriptionUbiquitin Isopeptidase Inhibitor I ≥98%
Packaging5mg
Price$107
Updated2026-04-30
Buy

ManufacturerCSNpharm
Product numberCSN21899
Product descriptionUbiquitinIsopeptidaseInhibitorI,G5
Packaging25mg
Price$265
Updated2021-12-16
Buy

ManufacturerCSNpharm
Product numberCSN21899
Product descriptionUbiquitinIsopeptidaseInhibitorI,G5
Packaging100mg
Price$836
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC10298
Product descriptionUbiquitin Isopeptidase Inhibitor I, G5 >98%
Packaging250mg
Price$900
Updated2026-05-24
Buy

ManufacturerDC Chemicals
Product numberDC10298
Product descriptionUbiquitin Isopeptidase Inhibitor I, G5 >98%
Packaging100mg
Price$450
Updated2026-05-24
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
ACHEMBLOCK	AD268620	Ubiquitin Isopeptidase Inhibitor I, G5 98%	25MG	$110	2026-05-27	Buy
ACHEMBLOCK	AD268620	Ubiquitin Isopeptidase Inhibitor I, G5 98%	100MG	$190	2026-05-27	Buy
ACHEMBLOCK	AD268620	Ubiquitin Isopeptidase Inhibitor I, G5 98%	250MG	$340	2026-05-27	Buy
AK Scientific	5032CP	UbiquitinIsopeptidaseInhibitorI,G5	5mg	$206	2021-12-16	Buy
ApexBio Technology	C3250	Ubiquitin Isopeptidase Inhibitor I	25mg	$347	2026-05-06	Buy
ApexBio Technology	C3250	Ubiquitin Isopeptidase Inhibitor I	10mg	$174	2026-05-06	Buy
ApexBio Technology	C3250	Ubiquitin Isopeptidase Inhibitor I	5mg	$100	2026-05-06	Buy
Biosynth	IEA47718	Ubiquitin Isopeptidase Inhibitor I, G5	50mg	$1117.5	2026-06-04	Buy
Biosynth	IEA47718	Ubiquitin Isopeptidase Inhibitor I, G5	100mg	$1555	2026-06-04	Buy
Cayman Chemical	21006	Ubiquitin Isopeptidase Inhibitor I ≥98%	25mg	$396	2026-04-30	Buy
Cayman Chemical	21006	Ubiquitin Isopeptidase Inhibitor I ≥98%	10mg	$193	2026-04-30	Buy
Cayman Chemical	21006	Ubiquitin Isopeptidase Inhibitor I ≥98%	5mg	$107	2026-04-30	Buy
CSNpharm	CSN21899	UbiquitinIsopeptidaseInhibitorI,G5	25mg	$265	2021-12-16	Buy
CSNpharm	CSN21899	UbiquitinIsopeptidaseInhibitorI,G5	100mg	$836	2021-12-16	Buy
DC Chemicals	DC10298	Ubiquitin Isopeptidase Inhibitor I, G5 >98%	250mg	$900	2026-05-24	Buy
DC Chemicals	DC10298	Ubiquitin Isopeptidase Inhibitor I, G5 >98%	100mg	$450	2026-05-24	Buy

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Properties

Melting point :233.5-234.5 °C
Boiling point :693.0±55.0 °C(Predicted)
Density :1.541±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C,unstable in solution, ready to use.
solubility :≤15mg/ml in DMSO;1mg/ml in dimethyl formamide
form :crystalline solid
color :Light yellow to yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ubiquitin isopeptidase inhibitor I induces caspase activation and apoptosis (IC₅₀ = ~1.7 μM) through a Bcl-2-dependent and apoptosome-independent mitochondrial pathway that selectively inhibits ubiquitin isopeptidase activity (IC₅₀ = ~30 μM). It has also been shown to induce necrosis in apoptosis-resistant DKO cells.

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Suppliers and manufacturers

career henan chemical co

$1.00
4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-1,1-dioxide CAS:108477-18-5

TargetMol Chemicals Inc.

$74.00
Ubiquitin Isopeptidase Inhibitor I, G5 CAS:108477-18-5

TargetMol Chemicals Inc.

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Nextpeptide Inc

InvivoChem

Aladdin Scientific VDM Biochemicals SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD Shanghai EFE Biological Technology Co., Ltd.

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4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-1,1-dioxide

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers