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ChemicalBook >> CAS DataBase List >> Doxorubicin hydrochloride

Doxorubicin hydrochloride

Doxorubicin hydrochloride price.
  • $25 - $1120
  • Product name: Doxorubicin hydrochloride
  • CAS: 25316-40-9
  • MF: C27H30ClNO11
  • MW: 579.98
  • EINECS:246-818-3
  • MDL Number:MFCD00077757
  • Synonyms:ADRIACIN;ADRIBLASTINA;ADRIBLASTINA HYDROCHLORIDE;ADRIAMYCIN HCL;ADRIAMYCIN HYDROCHLORIDE;(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride;14-HYDROXYDAUNOMYCIN HCL;14-HYDROXYDAUNOMYCIN HYDROCHLORIDE
19 prices
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Brand

  • Alfa Aesar
  • Cayman Chemical
  • Sigma-Aldrich
  • TCI Chemical

Package

  • d2975000
  • 5mg
  • 1mg
  • 5040420001
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 1ml
  • ManufacturerAlfa Aesar
  • Product numberJ64000
  • Product descriptionDoxorubicin hydrochloride
  • Packaging10mg
  • Price$189
  • Updated2021-03-22
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67209
  • Product descriptionDoxorubicin hydrochloride, 10 mg/ml in DMSO, sterile filtered
  • Packaging1ml
  • Price$403
  • Updated2021-03-22
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64000
  • Product descriptionDoxorubicin hydrochloride
  • Packaging50mg
  • Price$408
  • Updated2021-03-22
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67364
  • Product descriptionDoxorubicin hydrochloride, 10 mg/ml in distilled water, sterile filtered
  • Packaging1ml
  • Price$523
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number15007
  • Product descriptionDoxorubicin (hydrochloride) ≥98%
  • Packaging25mg
  • Price$88
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number15007
  • Product descriptionDoxorubicin (hydrochloride) ≥98%
  • Packaging50mg
  • Price$100
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number15007
  • Product descriptionDoxorubicin (hydrochloride) ≥98%
  • Packaging5mg
  • Price$25
  • Updated2021-03-22
  • Buy
  • ManufacturerCayman Chemical
  • Product number15007
  • Product descriptionDoxorubicin (hydrochloride) ≥98%
  • Packaging10mg
  • Price$45
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number44583
  • Product descriptionDoxorubicin hydrochloride suitable for fluorescence, 98.0-102.0% (HPLC)
  • Packaging1mg
  • Price$51
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD2975000
  • Product descriptionDoxorubicin hydrochloride European Pharmacopoeia (EP) Reference Standard
  • Packagingd2975000
  • Price$190
  • Updated2020-08-18
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD2975000
  • Product descriptionDoxorubicin hydrochloride European Pharmacopoeia (EP) Reference Standard
  • Packaging
  • Price$190
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD1515
  • Product descriptionDoxorubicin hydrochloride 98.0-102.0% (HPLC)
  • Packaging10mg
  • Price$252
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number44583
  • Product descriptionDoxorubicin hydrochloride suitable for fluorescence, 98.0-102.0% (HPLC)
  • Packaging10mg
  • Price$260
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHR1789
  • Product descriptionDoxorubicin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging200mg
  • Price$319
  • Updated2021-03-22
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number5.04042
  • Product descriptionInSolution Doxorubicin, Hydrochloride - CAS 25316-40-9 - Calbiochem
  • Packaging5040420001
  • Price$126
  • Updated2020-08-18
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number44583
  • Product descriptionDoxorubicin hydrochloride suitable for fluorescence, 98.0-102.0% (HPLC)
  • Packaging50mg
  • Price$914
  • Updated2021-03-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J64000 Doxorubicin hydrochloride 10mg $189 2021-03-22 Buy
Alfa Aesar J67209 Doxorubicin hydrochloride, 10 mg/ml in DMSO, sterile filtered 1ml $403 2021-03-22 Buy
Alfa Aesar J64000 Doxorubicin hydrochloride 50mg $408 2021-03-22 Buy
Alfa Aesar J67364 Doxorubicin hydrochloride, 10 mg/ml in distilled water, sterile filtered 1ml $523 2021-03-22 Buy
Cayman Chemical 15007 Doxorubicin (hydrochloride) ≥98% 25mg $88 2021-03-22 Buy
Cayman Chemical 15007 Doxorubicin (hydrochloride) ≥98% 50mg $100 2021-03-22 Buy
Cayman Chemical 15007 Doxorubicin (hydrochloride) ≥98% 5mg $25 2021-03-22 Buy
Cayman Chemical 15007 Doxorubicin (hydrochloride) ≥98% 10mg $45 2021-03-22 Buy
Sigma-Aldrich 44583 Doxorubicin hydrochloride suitable for fluorescence, 98.0-102.0% (HPLC) 1mg $51 2021-03-22 Buy
Sigma-Aldrich D2975000 Doxorubicin hydrochloride European Pharmacopoeia (EP) Reference Standard d2975000 $190 2020-08-18 Buy
Sigma-Aldrich D2975000 Doxorubicin hydrochloride European Pharmacopoeia (EP) Reference Standard $190 2021-03-22 Buy
Sigma-Aldrich D1515 Doxorubicin hydrochloride 98.0-102.0% (HPLC) 10mg $252 2021-03-22 Buy
Sigma-Aldrich 44583 Doxorubicin hydrochloride suitable for fluorescence, 98.0-102.0% (HPLC) 10mg $260 2021-03-22 Buy
Sigma-Aldrich PHR1789 Doxorubicin hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 200mg $319 2021-03-22 Buy
Sigma-Aldrich 5.04042 InSolution Doxorubicin, Hydrochloride - CAS 25316-40-9 - Calbiochem 5040420001 $126 2020-08-18 Buy
Sigma-Aldrich 44583 Doxorubicin hydrochloride suitable for fluorescence, 98.0-102.0% (HPLC) 50mg $914 2021-03-22 Buy

Properties

Melting point: :216 °C (dec.)(lit.)
alpha  :D20 +248±2° (c = 0.1 in methanol)
storage temp.  :2-8°C
solubility  :H2O: 10 mg/mL, clear, red-orange
pka :pKa 8.25±0.60 (Uncertain);8.43±0.70 (Uncertain);11.9±0.4 (Uncertain);12.95±0.1 (Uncertain);13.8±0.70 (Uncertain)
form  :solid
color  :orange to dark red
Water Solubility  :Soluble in water.
λmax :497nm(H2O)(lit.)
Merck  :14,3439
BRN  :4229251
InChIKey :MWWSFMDVAYGXBV-RUELKSSGSA-N
CAS DataBase Reference :25316-40-9(CAS DataBase Reference)
EPA Substance Registry System :Doxorubicin hydrochloride (25316-40-9)

Safety Information

Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.

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