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ChemicalBook >> CAS DataBase List >> 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione price.
  • $15 - $2130
  • Product name: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
  • CAS: 1104546-89-5
  • MF: C15H12N2O2
  • MW: 252.27
  • EINECS:
  • MDL Number:MFCD12912397
  • Synonyms:4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione;BYK 204165;4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione;PARP Inhibitor XIV ;4-(1-Methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinoline-1,3-dione;RT-017290;1,3(2H,4H)-Isoquinolinedione, 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-;BYK204165 >=98% (HPLC)
58 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA008Y1X
  • Product descriptionBYK204165 98%
  • Packaging25mg
  • Price$69
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008Y1X
  • Product descriptionBYK204165 98%
  • Packaging50mg
  • Price$108
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008Y1X
  • Product descriptionBYK204165 ≥98%
  • Packaging100mg
  • Price$206
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008Y1X
  • Product descriptionBYK204165 ≥98%
  • Packaging250mg
  • Price$451
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008Y1X
  • Product descriptionBYK204165 98%
  • Packaging10mg
  • Price$42
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008Y1X
  • Product descriptionBYK204165 ≥98%
  • Packaging5mg
  • Price$22
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008Y1X
  • Product descriptionBYK204165 98%
  • Packaging1mg
  • Price$15
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU109928
  • Product descriptionBYK204165 98.00%
  • Packaging25MG
  • Price$115
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU109928
  • Product descriptionBYK204165 98.00%
  • Packaging1G
  • Price$950
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU109928
  • Product descriptionBYK204165 98.00%
  • Packaging100MG
  • Price$300
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2830DC
  • Product description(4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione
  • Packaging5mg
  • Price$256
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2830DC
  • Product description(4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging25mg
  • Price$112
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging10mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging5mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1219188
  • Product description4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98%
  • Packaging50mg
  • Price$192
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008Y1X BYK204165 98% 25mg $69 2026-05-28 Buy
aablocks AA008Y1X BYK204165 98% 50mg $108 2026-05-28 Buy
aablocks AA008Y1X BYK204165 ≥98% 100mg $206 2026-05-28 Buy
aablocks AA008Y1X BYK204165 ≥98% 250mg $451 2026-05-28 Buy
aablocks AA008Y1X BYK204165 98% 10mg $42 2026-05-28 Buy
aablocks AA008Y1X BYK204165 ≥98% 5mg $22 2026-05-28 Buy
aablocks AA008Y1X BYK204165 98% 1mg $15 2026-05-28 Buy
ACHEMBLOCK U109928 BYK204165 98.00% 25MG $115 2026-05-27 Buy
ACHEMBLOCK U109928 BYK204165 98.00% 1G $950 2026-05-27 Buy
ACHEMBLOCK U109928 BYK204165 98.00% 100MG $300 2026-05-27 Buy
AK Scientific 2830DC (4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione 5mg $256 2021-12-16 Buy
AK Scientific 2830DC (4Z)-4-[(1-Methylpyrrol-2-yl)methylidene]isoquinoline-1,3-dione 1mg $139 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 25mg $112 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 10mg $72 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 5mg $42 2021-12-16 Buy
Ambeed A1219188 4-((1-Methyl-1H-pyrrol-2-yl)methylene)isoquinoline-1,3(2H,4H)-dione 98% 50mg $192 2021-12-16 Buy

Properties

Boiling point :492.5±45.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :9.30±0.20(Predicted)
form :powder
color :yellow
InChI :1S/C15H12N2O2/c1-17-8-4-5-10(17)9-13-11-6-2-3-7-12(11)14(18)16-15(13)19/h2-9H,1H3,(H,16,18,19)/b13-9-
InChIKey :BTYSIDSTHDDAJW-LCYFTJDESA-N
SMILES :Cn1cccc1\C=C2/C(=O)NC(=O)c3ccccc23

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

BYK204165, also known as PARP Inhibitor XIV, is a cell-permeable isoquinolinedione compound that potently and selectively inhibits poly (ADP-ribose) polymerase 1 (PARP1). PARP1 is a nuclear enzyme involved in the regulation of various cell processes such as differentiation, proliferation, and tumor transformation. It is also involved in the regulation of the molecular events involved in the recovery of cell from DNA damage. BYK204165’s potency is similar or higher than most current standard PARP-1 inhibitors (just slightly lower than PJ34), and it is 100-fold selective for PARP-1 over PARP-2.