9-keto Fluprostenol isopropyl ester
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- $88 - $866
- Product name: 9-keto Fluprostenol isopropyl ester
- CAS: 1219032-18-4
- MF: C26H33F3O6
- MW: 498.53
- EINECS:
- MDL Number:MFCD02259341
- Synonyms:(+)-9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC-ACID, ISOPROPYL ESTER;9-KETO FLUPROSTENOL ISOPROPYL ESTER;FLUPROSTENOL PROSTAGLANDIN E2 ISOPROPYL ESTER;Travoprost Impurity 16（9-keto Fluprostenol Isopropyl Ester）;9-Keto Travoprost;Travoprost Impurity 35;Travoprost Impurity 21;Travoprost 12
7 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number1006AH
- Product description(+)-9-oxo-11alpha,15R-Dihydroxy-16-(3-(trifluoromethyl)Phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oicacidisopropylester
- Packaging1mg
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1006AH
- Product description(+)-9-oxo-11alpha,15R-Dihydroxy-16-(3-(trifluoromethyl)Phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oicacidisopropylester
- Packaging5mg
- Price$532
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1006AH
- Product description(+)-9-oxo-11alpha,15R-Dihydroxy-16-(3-(trifluoromethyl)Phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oicacidisopropylester
- Packaging10mg
- Price$866
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0002293
- Product description(+)-9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID ISOPROPYL ESTER 95.00%
- Packaging5MG
- Price$502.76
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16782
- Product description9-keto Fluprostenol isopropyl ester ≥98%
- Packaging1mg
- Price$88
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16782
- Product description9-keto Fluprostenol isopropyl ester ≥98%
- Packaging5mg
- Price$389
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16782
- Product description9-keto Fluprostenol isopropyl ester ≥98%
- Packaging10mg
- Price$691
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1006AH | (+)-9-oxo-11alpha,15R-Dihydroxy-16-(3-(trifluoromethyl)Phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oicacidisopropylester | 1mg | $195 | 2021-12-16 | Buy |
| AK Scientific | 1006AH | (+)-9-oxo-11alpha,15R-Dihydroxy-16-(3-(trifluoromethyl)Phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oicacidisopropylester | 5mg | $532 | 2021-12-16 | Buy |
| AK Scientific | 1006AH | (+)-9-oxo-11alpha,15R-Dihydroxy-16-(3-(trifluoromethyl)Phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oicacidisopropylester | 10mg | $866 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0002293 | (+)-9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID ISOPROPYL ESTER 95.00% | 5MG | $502.76 | 2021-12-16 | Buy |
| Cayman Chemical | 16782 | 9-keto Fluprostenol isopropyl ester ≥98% | 1mg | $88 | 2024-03-01 | Buy |
| Cayman Chemical | 16782 | 9-keto Fluprostenol isopropyl ester ≥98% | 5mg | $389 | 2024-03-01 | Buy |
| Cayman Chemical | 16782 | 9-keto Fluprostenol isopropyl ester ≥98% | 10mg | $691 | 2024-03-01 | Buy |
Properties
Boiling point :583.6±50.0 °C(Predicted)
Density :1.241±0.06 g/cm3(Predicted)
solubility :DMF: 30 mg/ml; DMF:PBS (1:1): 500 μg/ml; DMSO: 20 mg/ml; Ethanol: 25 mg/ml
pka :13.32±0.20(Predicted)
Density :1.241±0.06 g/cm3(Predicted)
solubility :DMF: 30 mg/ml; DMF:PBS (1:1): 500 μg/ml; DMSO: 20 mg/ml; Ethanol: 25 mg/ml
pka :13.32±0.20(Predicted)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||||
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Description
Fluprostenol is a well-studied, potent analog of prostaglandin F2α (PGF2α) and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. Prostaglandin esters are known to be hydrolyzed in the eye to the corresponding free acids. However, the use of prostaglandin esters as prodrugs outside the eye is relatively unexplored. 9-keto Fluprostenol is an analog of PGE2 with structural modifications intended to give it a prolonged half-life and greater potency. 9-keto Fluprostenol isopropyl ester has the potential to act as an EP agonist in prodrug form. However, no studies on the pharmacology of this compound have been published to date. In addition 9-keto fluprostenol isopropyl ester is a potential metabolite of Travoprost, which is the Alcon trade name for fluprostenol isopropyl ester. In monkey cornea, this transformation was observed as a product of NADP+-dependent 15-hydroxyprostaglandin dehydrogenase when the closely related analog Latanoprost was used as a substrate. Certain F-series prostaglandins have been shown to be converted to the corresponding E-series compounds in rabbit liver and human platelet preparations.More related product prices
9-KETO FLUPROSTENOL 15(S)-FLUPROSTENOL (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Travoprost Acid 404830-45-1 3-Trifluoromethylphenol 5,6-trans Travoprost 15-KETO FLUPROSTENOL Travoprost 1420791-14-5 Ethyl bromoacetate IodoethaneRelated product price
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