Losartan carboxylic acid
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- $7 - $1750
- Product name: Losartan carboxylic acid
- CAS: 124750-92-1
- MF: C22H21ClN6O2
- MW: 436.89
- EINECS:1592732-453-0
- MDL Number:MFCD00871928
- Synonyms:AKOS 91941;2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID;’-biphenyl)-4-yl)methyl)- ;1h-imidazole-5-carboxylicacid,2-butyl-4-chloro-1-((2’-(14-tetrazol-5-yl)(1,1 ;1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid;1H-Imidazole-5-carboxylicacid, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-;2-Butyl-4-chloro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicAcid;EXP 317
33 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50MG
- 100mg
- 250mg
- 50
- 10
- 1g
- ManufacturerAK Scientific
- Product number8776AJ
- Product descriptionLosartancarboxylicacid
- Packaging250mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA401868
- Product descriptionLosartancarboxylicacid 97%
- Packaging1mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA401868
- Product descriptionLosartancarboxylicacid 97%
- Packaging5mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA401868
- Product descriptionLosartancarboxylicacid 97%
- Packaging10mg
- Price$21
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA401868
- Product descriptionLosartancarboxylicacid 97%
- Packaging100mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA401868
- Product descriptionLosartancarboxylicacid 97%
- Packaging250mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA401868
- Product descriptionLosartancarboxylicacid 97%
- Packaging1g
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0002671
- Product descriptionLOSARTAN CARBOXYLIC ACID 95.00%
- Packaging10MG
- Price$535
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0002671
- Product descriptionLOSARTAN CARBOXYLIC ACID 95.00%
- Packaging50MG
- Price$975
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0002671
- Product descriptionLOSARTAN CARBOXYLIC ACID 95.00%
- Packaging100MG
- Price$1750
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3065
- Product descriptionLosartanCarboxylicAcid
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3065
- Product descriptionLosartanCarboxylicAcid
- Packaging10mg
- Price$194
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15957
- Product descriptionLosartan Carboxylic Acid ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15957
- Product descriptionLosartan Carboxylic Acid ≥98%
- Packaging5mg
- Price$98
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15957
- Product descriptionLosartan Carboxylic Acid ≥98%
- Packaging10mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15957
- Product descriptionLosartan Carboxylic Acid ≥98%
- Packaging50mg
- Price$704
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8776AJ | Losartancarboxylicacid | 250mg | $138 | 2021-12-16 | Buy |
| Ambeed | A401868 | Losartancarboxylicacid 97% | 1mg | $7 | 2021-12-16 | Buy |
| Ambeed | A401868 | Losartancarboxylicacid 97% | 5mg | $16 | 2021-12-16 | Buy |
| Ambeed | A401868 | Losartancarboxylicacid 97% | 10mg | $21 | 2021-12-16 | Buy |
| Ambeed | A401868 | Losartancarboxylicacid 97% | 100mg | $46 | 2021-12-16 | Buy |
| Ambeed | A401868 | Losartancarboxylicacid 97% | 250mg | $86 | 2021-12-16 | Buy |
| Ambeed | A401868 | Losartancarboxylicacid 97% | 1g | $266 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0002671 | LOSARTAN CARBOXYLIC ACID 95.00% | 10MG | $535 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0002671 | LOSARTAN CARBOXYLIC ACID 95.00% | 50MG | $975 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0002671 | LOSARTAN CARBOXYLIC ACID 95.00% | 100MG | $1750 | 2021-12-16 | Buy |
| ApexBio Technology | C3065 | LosartanCarboxylicAcid | 5mg | $120 | 2021-12-16 | Buy |
| ApexBio Technology | C3065 | LosartanCarboxylicAcid | 10mg | $194 | 2021-12-16 | Buy |
| Cayman Chemical | 15957 | Losartan Carboxylic Acid ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 15957 | Losartan Carboxylic Acid ≥98% | 5mg | $98 | 2024-03-01 | Buy |
| Cayman Chemical | 15957 | Losartan Carboxylic Acid ≥98% | 10mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 15957 | Losartan Carboxylic Acid ≥98% | 50mg | $704 | 2024-03-01 | Buy |
Properties
Melting point :130-132°C
Boiling point :707.8±70.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Dimethylformamide, Dimethyl Sulfoxide, Methanol
form :Solid
pka :0.79±0.50(Predicted)
color :Light-Yellow
InChIKey :ZEUXAIYYDDCIRX-UHFFFAOYSA-N
SMILES :C1(CCCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C(C(O)=O)=C(Cl)N=1
Boiling point :707.8±70.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Dimethylformamide, Dimethyl Sulfoxide, Methanol
form :Solid
pka :0.79±0.50(Predicted)
color :Light-Yellow
InChIKey :ZEUXAIYYDDCIRX-UHFFFAOYSA-N
SMILES :C1(CCCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C(C(O)=O)=C(Cl)N=1
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
| Hazard statements: |
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Description
Losartan is an antagonist of the angiotensin II receptor, type 1 (AT1) (Ki = 5-20 nM). It has an attenuating effect on vein graft atherosclerosis in rabbits and effectively reduces arterial blood pressure in rats. In humans, losartan controls hypertension while protecting renal function. Losartan carboxylic acid is a physiologically active metabolite of losartan, produced by cytochrome P450 isoforms in the liver. Like the parent compound, losartan carboxylic acid is a potent AT1 antagonist (Kis = 0.57 and 0.67 nM for rat and human forms, respectively), producing a depressor response and vasodilatation. When administered intravenously, losartan carboxylic acid is more potent and has a longer duration of action than losartan. However, the metabolite has very low oral bioavailability. Losartan, but not its metabolite, inhibits platelet aggregation in vitro.More related product prices
Losartan potassium Irbesartan Valsartan Candesartan cilexetil Ethyl acetate Trityl losartan LosartanRelated product price
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$5-541 - Irbesartan
$5-1200 - Valsartan
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Suppliers and manufacturers
career henan chemical co
![2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID](https://img.chemicalbook.com/ProductImageEN/2020-1/small/dd5a4f81-83bd-420f-9ace-dcb08eadd082.png)
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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$1.00 /1KG
2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID CAS:124750-92-1
2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID CAS:124750-92-1
![2-BUTYL-4-CHLORO-1-[(2'-(1-H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL)METHYL]-1-H-IMIDAZOLE-5-CARBOXYLIC ACID USP/EP/BP](/ProductImageEN/2021-08/small/a0f97e24-32ed-4aa0-85fc-905bc3de1c3f.jpg){kind=small}