Candesartan cilexetil
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- $6 - $1420
- Product name: Candesartan cilexetil
- CAS: 145040-37-5
- MF: C33H34N6O6
- MW: 610.66
- EINECS:627-030-2
- MDL Number:MFCD00871371
- Synonyms:1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester;Candesantan Cilexetil;1-(((cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate;1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2;1-(Cyclohexyloxycarbonyloxy)ethyl 1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-ethoxy-1H-b;1-(((cyclohexyloxy)carbonyl)oxy)ethylester,(+-)-henyl)-4-yl)methyl) ;1h-benzimidazole-7-carboxylicacid,2-ethoxy-1-((2’-(1h-tetrazol-5-yl)(1,1’-bip ;tcv116
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Brand
- AHH
- AK Scientific
- Ambeed
- Arctom
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- y0001387
- 200mg
- y0001389
- 0.1g
- y0001388
- 10
- 50mg
- 100mg
- 50
- 5mg
- 10mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- 25g
- 100g
- ManufacturerAHH
- Product numberAPI-1551
- Product descriptionCandesartan cilexetil 98%
- Packaging0.1g
- Price$720
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10436
- Product descriptionCandesartan cilexetil
- Packaging100mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10436
- Product descriptionCandesartan cilexetil
- Packaging1g
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA259269
- Product description1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+%
- Packaging10mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA259269
- Product description1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+%
- Packaging50mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA259269
- Product description1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+%
- Packaging1g
- Price$11
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA259269
- Product description1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+%
- Packaging5g
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA259269
- Product description1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+%
- Packaging10g
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA259269
- Product description1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+%
- Packaging25g
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA259269
- Product description1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+%
- Packaging100g
- Price$477
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS496974
- Product descriptionCandesartan cilexetil ≥98%
- Packaging10mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS496974
- Product descriptionCandesartan cilexetil ≥98%
- Packaging50mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS496974
- Product descriptionCandesartan cilexetil ≥98%
- Packaging1g
- Price$31
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS496974
- Product descriptionCandesartan cilexetil ≥98%
- Packaging5g
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS496974
- Product descriptionCandesartan cilexetil ≥98%
- Packaging10g
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS496974
- Product descriptionCandesartan cilexetil ≥98%
- Packaging25g
- Price$234
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1551 | Candesartan cilexetil 98% | 0.1g | $720 | 2021-12-16 | Buy |
| AK Scientific | J10436 | Candesartan cilexetil | 100mg | $95 | 2021-12-16 | Buy |
| AK Scientific | J10436 | Candesartan cilexetil | 1g | $251 | 2021-12-16 | Buy |
| Ambeed | A259269 | 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+% | 10mg | $6 | 2021-12-16 | Buy |
| Ambeed | A259269 | 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+% | 50mg | $8 | 2021-12-16 | Buy |
| Ambeed | A259269 | 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+% | 1g | $11 | 2021-12-16 | Buy |
| Ambeed | A259269 | 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+% | 5g | $32 | 2021-12-16 | Buy |
| Ambeed | A259269 | 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+% | 10g | $60 | 2021-12-16 | Buy |
| Ambeed | A259269 | 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+% | 25g | $130 | 2021-12-16 | Buy |
| Ambeed | A259269 | 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate 98+% | 100g | $477 | 2021-12-16 | Buy |
| Arctom | AS496974 | Candesartan cilexetil ≥98% | 10mg | $6 | 2021-12-16 | Buy |
| Arctom | AS496974 | Candesartan cilexetil ≥98% | 50mg | $10 | 2021-12-16 | Buy |
| Arctom | AS496974 | Candesartan cilexetil ≥98% | 1g | $31 | 2021-12-16 | Buy |
| Arctom | AS496974 | Candesartan cilexetil ≥98% | 5g | $65 | 2021-12-16 | Buy |
| Arctom | AS496974 | Candesartan cilexetil ≥98% | 10g | $128 | 2021-12-16 | Buy |
| Arctom | AS496974 | Candesartan cilexetil ≥98% | 25g | $234 | 2021-12-16 | Buy |
Properties
Melting point :168-170?C
Boiling point :843.3±75.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
pka :pKa 3.55 (H2O t=25.0 I=0.025) (Uncertain);5.91(H2O t=25.0 I=0.025) (Uncertain)
form :powder
color :white to beige
λmax :304nm(EtOH)(lit.)
Merck :14,1739
BCS Class :2
InChIKey :GHOSNRCGJFBJIB-UHFFFAOYSA-N
SMILES :C1(OCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C2=C(C(OC(OC(OC3CCCCC3)=O)C)=O)C=CC=C2N=1
CAS DataBase Reference :145040-37-5(CAS DataBase Reference)
Boiling point :843.3±75.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
pka :pKa 3.55 (H2O t=25.0 I=0.025) (Uncertain);5.91(H2O t=25.0 I=0.025) (Uncertain)
form :powder
color :white to beige
λmax :304nm(EtOH)(lit.)
Merck :14,1739
BCS Class :2
InChIKey :GHOSNRCGJFBJIB-UHFFFAOYSA-N
SMILES :C1(OCC)N(CC2=CC=C(C3=CC=CC=C3C3=NNN=N3)C=C2)C2=C(C(OC(OC(OC3CCCCC3)=O)C)=O)C=CC=C2N=1
CAS DataBase Reference :145040-37-5(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Candesartan cilexetil is a kind of prodrug being hydrolyzed to candesartan during absorption from the gastrointestinal tract. It appears as a white or off-white powder with a molecular weight of 610.67. It is soluble in methanol but insoluble in water. It is a kind of selective AT1 subtype angiotensin II receptor antagonist, mainly used for the treatment of hypertension and heart failure. Candesartan cilexetil takes effects through selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland, further blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Therefore, its mode of action is not through interfering with the pathways for angiotensin II synthesis. Candesartan cilexetil may lead to various kinds of adverse reactions including headache, back pain, dizziness, upper respiratory tract infection, pharyngitis, rhinitis, bronchitis, coughing, sinusitis, nausea, abdominal pain, diarrhea, vomiting, arthralgia and albuminuria. It should be warned that candesartan cilexetil might have remarkable fetal toxicity. Therefore, upon pregnancy, candesartan cilexetil should be discontinued. It could also cause hypotension for heart-failure patients.More related product prices
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Suppliers and manufacturers
APOLLO HEALTHCARE RESOURCES
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Jiangsu Zhongbang Pharmaceutical Co., Ltd.
