2-(1-Phenyl-cyclopropylamino)-pyrimidine-5-carboxylic acid hydroxyamide
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- $62 - $1000
- Product name: 2-(1-Phenyl-cyclopropylamino)-pyrimidine-5-carboxylic acid hydroxyamide
- CAS: 1375465-91-0
- MF: C14H14N4O2
- MW: 270.29
- EINECS:
- MDL Number:MFCD28347706
- Synonyms:2-(1-Phenyl-cyclopropylamino)-pyrimidine-5-carboxylic acid hydroxyamide;ACY-738;N-Hydroxy-2-[(1-phenylcyclopropyl)amino]-5-pyrimidinecarboxamide;ACY 738; ACY738;2-(1-phenylcyclopropylamino)-N-hydroxypyrimidine-5-carboxamide;ACY738;ACY-738;ACY 738;CS-2244;5-Pyrimidinecarboxamide, N-hydroxy-2-[(1-phenylcyclopropyl)amino]-
18 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number4633DN
- Product descriptionCID57381425
- Packaging5mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4633DN
- Product descriptionCID57381425
- Packaging50mg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28282
- Product descriptionACY-738
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28282
- Product descriptionACY-738
- Packaging5mg
- Price$239
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28282
- Product descriptionACY-738
- Packaging10mg
- Price$419
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28282
- Product descriptionACY-738
- Packaging25mg
- Price$819
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM244162
- Product descriptionN-Hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide 95+%
- Packaging10mg
- Price$107
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM244162
- Product descriptionN-Hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide 95+%
- Packaging50mg
- Price$295
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM244162
- Product descriptionN-Hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide 95+%
- Packaging100mg
- Price$442
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5149
- Product descriptionACY-738 98.75%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5149
- Product descriptionACY-738 98.75%
- Packaging10mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5149
- Product descriptionACY-738 98.75%
- Packaging50mg
- Price$588
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5149
- Product descriptionACY-738 98.75%
- Packaging100mg
- Price$780
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003696
- Product descriptionACY-738 98+%
- Packaging10mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003696
- Product descriptionACY-738 98+%
- Packaging25mg
- Price$493
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003696
- Product descriptionACY-738 98+%
- Packaging50mg
- Price$840
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4633DN | CID57381425 | 5mg | $144 | 2021-12-16 | Buy |
| AK Scientific | 4633DN | CID57381425 | 50mg | $455 | 2021-12-16 | Buy |
| Cayman Chemical | 28282 | ACY-738 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 28282 | ACY-738 | 5mg | $239 | 2024-03-01 | Buy |
| Cayman Chemical | 28282 | ACY-738 | 10mg | $419 | 2024-03-01 | Buy |
| Cayman Chemical | 28282 | ACY-738 | 25mg | $819 | 2024-03-01 | Buy |
| Chemenu | CM244162 | N-Hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide 95+% | 10mg | $107 | 2021-12-16 | Buy |
| Chemenu | CM244162 | N-Hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide 95+% | 50mg | $295 | 2021-12-16 | Buy |
| Chemenu | CM244162 | N-Hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide 95+% | 100mg | $442 | 2021-12-16 | Buy |
| ChemScene | CS-5149 | ACY-738 98.75% | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-5149 | ACY-738 98.75% | 10mg | $216 | 2021-12-16 | Buy |
| ChemScene | CS-5149 | ACY-738 98.75% | 50mg | $588 | 2021-12-16 | Buy |
| ChemScene | CS-5149 | ACY-738 98.75% | 100mg | $780 | 2021-12-16 | Buy |
| Crysdot | CD31003696 | ACY-738 98+% | 10mg | $290 | 2021-12-16 | Buy |
| Crysdot | CD31003696 | ACY-738 98+% | 25mg | $493 | 2021-12-16 | Buy |
| Crysdot | CD31003696 | ACY-738 98+% | 50mg | $840 | 2021-12-16 | Buy |
Properties
Density :1.433±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:32.0(Max Conc. mg/mL);118.39(Max Conc. mM)
form :A crystalline solid
pka :7.75±0.10(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:32.0(Max Conc. mg/mL);118.39(Max Conc. mM)
form :A crystalline solid
pka :7.75±0.10(Predicted)
Safety Information
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Description
ACY-738 is an inhibitor of histone deacetylase 6 (HDAC6; IC50 = 1.7 nM). It is selective for HDAC6 over HDAC1-3 (IC50s = 94, 128, and 218 nM, respectively). ACY-738 (5 mg/kg) increases acetylation of α-tubulin in mouse brain. It increases exploratory activity in a novel open-field test and reduces immobility time in a tail suspension test in wild-type, but not neural cell-selective HDAC6 knockout, mice when administered at a dose of 50 mg/kg, indicating anxiolytic and antidepressant-like activity, respectively. ACY-738 (100 mg/kg in the diet) attenuates decreases in caudal nerve sensory nerve action potential (SNAP) amplitude and increases in hind paw mechanical hypersensitivity in a mouse model of peripheral neuropathy induced by vincristine . It decreases hepatorenal cystogenesis in a rat model of polycystic liver disease when administered at a dose of 30 mg/kg.Related product price
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Suppliers and manufacturers
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TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
$9.80 /1.79999995231628KG
2-(1-Phenyl-cyclopropylamino)-pyrimidine-5-carboxylic acid hydroxyamide CAS:1375465-91-0
2-(1-Phenyl-cyclopropylamino)-pyrimidine-5-carboxylic acid hydroxyamide CAS:1375465-91-0