(3β)-26,27-Dinorcholest-5-en-24-yne-3,20-diol

$72 - $1073
Product name: (3β)-26,27-Dinorcholest-5-en-24-yne-3,20-diol
CAS: 1397692-46-4
MF: C25H38O2
MW: 370.57
EINECS:
MDL Number:
Synonyms:(3β)-26,27-Dinorcholest-5-en-24-yne-3,20-diol;SCMAJJQBADBBSM-CMJRPVKTSA-N;Nat-20(S)-yne;Nat-20(S)-yne Exclusive;26,27-Dinorcholest-5-en-24-yne-3,20-diol, (3β)-;Nat20(S)yne,Nat 20(S) yne;(3β)-26,27-Dinorcholest-5-en-24-yne-3,20-diol, CAS 1397692-46-4

Price7 Properties Safety Information Description

7 prices

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Brand

aablocks
American Custom Chemicals Corporation
Cayman Chemical
TRC

Package

1mg
5MG
10mg
25mg

Manufactureraablocks
Product numberAA009F61
Product descriptionNat-20(S)-yne
Packaging1mg
Price$604
Updated2026-05-28
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberSHG0005206
Product descriptionNAT-20-(S)YNE 95.00%
Packaging5MG
Price$498.72
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number9001369
Product descriptionNat-20(S)-yne ≥90%
Packaging10mg
Price$537
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number9001369
Product descriptionNat-20(S)-yne ≥90%
Packaging1mg
Price$72
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number9001369
Product descriptionNat-20(S)-yne ≥90%
Packaging5mg
Price$304
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number9001369
Product descriptionNat-20(S)-yne ≥90%
Packaging25mg
Price$1073
Updated2026-04-30
Buy

ManufacturerTRC
Product numberD480430
Product description(3β)-26,27-Dinorcholest-5-en-24-yne-3,20-diol
Packaging10mg
Price$395
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA009F61	Nat-20(S)-yne	1mg	$604	2026-05-28	Buy
American Custom Chemicals Corporation	SHG0005206	NAT-20-(S)YNE 95.00%	5MG	$498.72	2021-12-16	Buy
Cayman Chemical	9001369	Nat-20(S)-yne ≥90%	10mg	$537	2026-04-30	Buy
Cayman Chemical	9001369	Nat-20(S)-yne ≥90%	1mg	$72	2026-04-30	Buy
Cayman Chemical	9001369	Nat-20(S)-yne ≥90%	5mg	$304	2026-04-30	Buy
Cayman Chemical	9001369	Nat-20(S)-yne ≥90%	25mg	$1073	2026-04-30	Buy
TRC	D480430	(3β)-26,27-Dinorcholest-5-en-24-yne-3,20-diol	10mg	$395	2021-12-16	Buy

Properties

Boiling point :510.0±25.0 °C(Predicted)
Density :1.08±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 14 mg/ml; DMSO: 0.5 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :14.68±0.29(Predicted)

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors. 20(S)-hydroxy Cholesterol (20(S)-OHC) is an oxysterol which binds SMO and activates hedgehog signaling (EC₅₀ = 3 μM), and this activation is selective for the nat-20(S)-OHC enantiomer. Nat-20(S)-OHC synergizes with the SMO agonist SAG, suggesting an allosteric effect. Nat-20(S)-yne is a form of nat-20(S)-OHC with a terminal alkyne group, which can be used in linking reactions known as click chemistry. Click chemistry involves highly dependable and specific azide-alkyne bioconjugation reactions and can be used to capture or immobilize bioactive molecules. Thus, nat-20(S)-yne has been conjugated with magnetic beads to demonstrate that nat-20(S)-OHC directly binds SMO.

Suppliers and manufacturers

TargetMol Chemicals Inc.

$218.00
Nat-20(S)-yne CAS:1397692-46-4

J & K SCIENTIFIC LTD. BOC Sciences Shanghai TaoSu Biochemical Technology Co., Ltd. Shanghai Hongye Biotechnology Co. Ltd Shenzhen Polymeri Biochemical Technology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd. Energy Chemical TargetMol Chemicals Inc. Shanghai Yifei Biotechnology Co. , Ltd.

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