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ChemicalBook >> CAS DataBase List >> PF 06465469 Discontinued See A191400

PF 06465469 Discontinued See A191400

PF 06465469 Discontinued See A191400 price.
  • $115.5 - $2400
  • Product name: PF 06465469 Discontinued See A191400
  • CAS: 1407966-77-1
  • MF: C30H33N7O2
  • MW: 523.63
  • EINECS:
  • MDL Number:MFCD23381175
  • Synonyms:PF 06465469 Discontinued See A191400;(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-aMino-1H-pyrazolo[3,4-d]pyriMidin-3-yl]-N-(4-isopropyl-5-Methylphenyl)benzaMide;PF 06465469;3-[4-Amino-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-[3-methyl-4-(1-methylethyl)phenyl]-benzamide;(R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide;Benzamide, 3-[4-amino-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-[3-methyl-4-(1-methylethyl)phenyl]-;PF06465469,PF 06465469;3-[4-amino-1-[(3R)-1-prop-2-enoyl-3-piperidyl]pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-3-methyl-phenyl)benzamide
Price12 Properties Safety Information Description
12 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10
  • 50
  • 2.5mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001576
  • Product descriptionPF-06465469 95.00%
  • Packaging5MG
  • Price$499.26
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5691
  • Product descriptionPF06465469
  • Packaging10mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5691
  • Product descriptionPF06465469
  • Packaging50mg
  • Price$1809
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2110
  • Product descriptionPF06465469 99%
  • Packaging5mg
  • Price$115.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029959
  • Product descriptionPF-06465469 98.31%
  • Packaging5mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029959
  • Product descriptionPF-06465469 98.31%
  • Packaging10mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number49407
  • Product description(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
  • Packaging50mg
  • Price$2400
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0209
  • Product descriptionPF-06465469 ≥97% (HPLC)
  • Packaging5mg
  • Price$128
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0209
  • Product descriptionPF-06465469 ≥97% (HPLC)
  • Packaging25mg
  • Price$496
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number4710
  • Product descriptionPF06465469 ≥95%(HPLC)
  • Packaging10
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4710
  • Product descriptionPF06465469 ≥95%(HPLC)
  • Packaging50
  • Price$1208
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA191400
  • Product description(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
  • Packaging2.5mg
  • Price$385
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0001576 PF-06465469 95.00% 5MG $499.26 2021-12-16 Buy
ApexBio Technology B5691 PF06465469 10mg $450 2021-12-16 Buy
ApexBio Technology B5691 PF06465469 50mg $1809 2021-12-16 Buy
Axon Medchem Axon2110 PF06465469 99% 5mg $115.5 2021-12-16 Buy
ChemScene CS-0029959 PF-06465469 98.31% 5mg $220 2021-12-16 Buy
ChemScene CS-0029959 PF-06465469 98.31% 10mg $340 2021-12-16 Buy
Medical Isotopes, Inc. 49407 (R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide 50mg $2400 2021-12-16 Buy
Sigma-Aldrich PZ0209 PF-06465469 ≥97% (HPLC) 5mg $128 2024-03-01 Buy
Sigma-Aldrich PZ0209 PF-06465469 ≥97% (HPLC) 25mg $496 2024-03-01 Buy
Tocris 4710 PF06465469 ≥95%(HPLC) 10 $300 2021-12-16 Buy
Tocris 4710 PF06465469 ≥95%(HPLC) 50 $1208 2021-12-16 Buy
TRC A191400 (R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide 2.5mg $385 2021-12-16 Buy

Properties

Melting point :209-212°C
Boiling point :730.2±60.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :12.83±0.70(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide is a potential covalent inhibitor of Interleukin-2 Inducible T Cell KInase (Itk). Itk is a member of the TEC-kinase family and is associated with the induction of T cell proliferation and drives cytokines through NFATc.

Suppliers and manufacturers

TargetMol Chemicals Inc.
InvivoChem
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific J & K SCIENTIFIC LTD. Chemsky（shanghai）International Co.,Ltd. Shanghai TaoSu Biochemical Technology Co., Ltd. EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. Shanghai Rechem science Co., Ltd.