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ChemicalBook >> CAS DataBase List >> N-((4-(4-phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide

N-((4-(4-phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide

N-((4-(4-phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide price.
  • $32 - $6476
  • Product name: N-((4-(4-phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide
  • CAS: 1428327-31-4
  • MF: C28H32N4O2S
  • MW: 488.64
  • EINECS:-0
  • MDL Number:MFCD28334214
  • Synonyms:N-((4-(4-phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide;JNJ-479655;N-[[4-(4-PHENYLPIPERAZIN-1-YL)OXAN-4-YL]METHYL]-2-PHENYLSULFANYLPYRIDINE-3-CARBOXAMIDE;JNJ-47965567 (JNJ47965567);2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide;3-Pyridinecarboxamide, 2-(phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl]-;JNJ-47965567 >=98% (HPLC);JNJ-47965567
Price25 Properties Safety Information Description
25 prices
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  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
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  • 5mg
  • 10mg
  • 1mg
  • 10
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product number2852DS
  • Product descriptionN-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide
  • Packaging10mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA720722
  • Product descriptionN-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide 97%
  • Packaging100mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA720722
  • Product descriptionN-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide 97%
  • Packaging250mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA720722
  • Product descriptionN-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide 97%
  • Packaging1g
  • Price$866
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21895
  • Product descriptionJNJ-47965567 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21895
  • Product descriptionJNJ-47965567 ≥98%
  • Packaging5mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21895
  • Product descriptionJNJ-47965567 ≥98%
  • Packaging10mg
  • Price$199
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21895
  • Product descriptionJNJ-47965567 ≥98%
  • Packaging25mg
  • Price$420
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM110496
  • Product descriptionJNJ-47965567 97%
  • Packaging100mg
  • Price$632
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM110496
  • Product descriptionJNJ-47965567 97%
  • Packaging250mg
  • Price$996
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021301
  • Product descriptionJNJ-47965567 98.63%
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021301
  • Product descriptionJNJ-47965567 98.63%
  • Packaging10mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021301
  • Product descriptionJNJ-47965567 98.63%
  • Packaging25mg
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0021301
  • Product descriptionJNJ-47965567 98.63%
  • Packaging50mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11258381
  • Product descriptionJNJ47965567 97%
  • Packaging100mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11258381
  • Product descriptionJNJ47965567 97%
  • Packaging250mg
  • Price$820
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2852DS N-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide 10mg $320 2021-12-16 Buy
Ambeed A720722 N-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide 97% 100mg $230 2021-12-16 Buy
Ambeed A720722 N-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide 97% 250mg $345 2021-12-16 Buy
Ambeed A720722 N-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide 97% 1g $866 2021-12-16 Buy
Cayman Chemical 21895 JNJ-47965567 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 21895 JNJ-47965567 ≥98% 5mg $109 2024-03-01 Buy
Cayman Chemical 21895 JNJ-47965567 ≥98% 10mg $199 2024-03-01 Buy
Cayman Chemical 21895 JNJ-47965567 ≥98% 25mg $420 2024-03-01 Buy
Chemenu CM110496 JNJ-47965567 97% 100mg $632 2021-12-16 Buy
Chemenu CM110496 JNJ-47965567 97% 250mg $996 2021-12-16 Buy
ChemScene CS-0021301 JNJ-47965567 98.63% 5mg $100 2021-12-16 Buy
ChemScene CS-0021301 JNJ-47965567 98.63% 10mg $195 2021-12-16 Buy
ChemScene CS-0021301 JNJ-47965567 98.63% 25mg $395 2021-12-16 Buy
ChemScene CS-0021301 JNJ-47965567 98.63% 50mg $720 2021-12-16 Buy
Crysdot CD11258381 JNJ47965567 97% 100mg $520 2021-12-16 Buy
Crysdot CD11258381 JNJ47965567 97% 250mg $820 2021-12-16 Buy
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Properties

storage temp. :2-8°C
solubility :DMF:30.0(Max Conc. mg/mL);61.39(Max Conc. mM)
DMSO:59.62(Max Conc. mg/mL);122.01(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.51(Max Conc. mM)
Ethanol:12.5(Max Conc. mg/mL);25.58(Max Conc. mM) form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

JNJ-47965567 is a selective antagonist of the purinergic receptor P2X subtype 7 (P2X7), a ligand-gated ion channel. Activation of P2X receptors by BzATP induces calcium flux, which is reduced by JNJ-47965567 in 1321N1 cells transfected with recombinant P2X7 human, macaque, dog, rat, or mouse protein with pIC50s of 8.3, 8.6, 8.5, 7.2, or 7.5, respectively. JNJ-47965567 suppresses neonatal hypoxia-induced seizures in mice and has some anticonvulsant properties in rats. It also reduces spontaneous seizures in epileptic mice even after treatment is stopped.

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