1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyridine-3-carbonitrile
![1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyridine-3-carbonitrile price.](/CAS/20180703/GIF/1449747-00-5.gif)
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- $32 - $1900
- Product name: 1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyridine-3-carbonitrile
- CAS: 1449747-00-5
- MF: C21H19N3O2
- MW: 345.39
- EINECS:
- MDL Number:MFCD28100815
- Synonyms:1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-ethyl]-6-oxo-1,6-dihydro-pyridine-3-carbonitrile;CYM-5520;1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-;1-[2-(1-benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-6-oxopyridine-3-carbonitrile;Inhibitor,osteoporosis,LPL Receptor,inhibit,allosteric,Lysophospholipid Receptor,CYM5520,CYM-5520,S1PR2
12 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 50
- 1mg
- 5mg
- 10mg
- 25mg
- 10
- 1g
- ManufacturerAK Scientific
- Product number2810DC
- Product description1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-6-oxopyridine-3-carbonitrile
- Packaging5mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5098
- Product descriptionCYM5520
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17638
- Product descriptionCYM 5520 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17638
- Product descriptionCYM 5520 ≥95%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17638
- Product descriptionCYM 5520 ≥95%
- Packaging10mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC43032
- Product descriptionCYM-5520 >98%
- Packaging1g
- Price$1900
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number92157
- Product descriptionCYM-5520
- Packaging1mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1014
- Product descriptionCYM-5520 ≥98% (HPLC)
- Packaging5mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1014
- Product descriptionCYM-5520 ≥98% (HPLC)
- Packaging25mg
- Price$498
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number5418
- Product descriptionCYM5520 ≥99%(HPLC)
- Packaging10
- Price$171
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5418
- Product descriptionCYM5520 ≥99%(HPLC)
- Packaging50
- Price$717
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC991495
- Product descriptionCYM-5520
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2810DC | 1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-6-oxopyridine-3-carbonitrile | 5mg | $201 | 2021-12-16 | Buy |
| ApexBio Technology | C5098 | CYM5520 | 5mg | $104 | 2021-12-16 | Buy |
| Cayman Chemical | 17638 | CYM 5520 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17638 | CYM 5520 ≥95% | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 17638 | CYM 5520 ≥95% | 10mg | $166 | 2024-03-01 | Buy |
| DC Chemicals | DC43032 | CYM-5520 >98% | 1g | $1900 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 92157 | CYM-5520 | 1mg | $350 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1014 | CYM-5520 ≥98% (HPLC) | 5mg | $120 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1014 | CYM-5520 ≥98% (HPLC) | 25mg | $498 | 2024-03-01 | Buy |
| Tocris | 5418 | CYM5520 ≥99%(HPLC) | 10 | $171 | 2021-12-16 | Buy |
| Tocris | 5418 | CYM5520 ≥99%(HPLC) | 50 | $717 | 2021-12-16 | Buy |
| TRC | C991495 | CYM-5520 | 10mg | $140 | 2021-12-16 | Buy |
Properties
Boiling point :580.5±50.0 °C(Predicted)
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :-2.80±0.70(Predicted)
form :powder
color :white to beige
Density :1.16±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :-2.80±0.70(Predicted)
form :powder
color :white to beige
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Sphingosine-1-phosphate (S1P; ) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P2 has been implicated in multiple biological functions, including Rho activation, inhibition of Rac and cell migration, and in “feed forward” autocrine signaling in NF-κB survival signaling of tumor cells. CYM 5520 is a noncompetitive allosteric agonist of S1P2 (EC50 = 0.48 μM) that does not display agonist activity towards S1P1, S1P3, S1P4, or S1P5.Suppliers and manufacturers
TargetMol Chemicals Inc.
Labnetwork lnc.
Nantong HI-FUTURE Biology Co., Ltd.
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
Guangzhou Isun Pharmaceutical Co., Ltd
Sigma-Aldrich
Shanghai Lollane Biological Technology Co.,Ltd.
Pharmacodia (Beijing) Co.,Ltd